HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
159 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

Have Multiple Myeloma. Prescribed Pomalyst. Will Drop In Blood Levels?

I have multiple myeloma and was prescribed pomalyst(celgene) 4mg with dex. I'm 5'5" weigh 95 lbs. and am 75 yrs old. What are the weight guidelines for this drug? Can't find this information in any of Celgene's patient studies. Since this drug can cause a significant drop in various blood levels, this is a concern. I have been on several chemo drugs. My oncologist doesn't have the answer.
Wed, 12 Jun 2013
Report Abuse
General & Family Physician 's  Response
Hello,
POMALYST is indicated for patients with multiple myeloma who have received at least two prior therapies  and have demonstrated disease progression on or within 60 days of completion of the last therapy. 

The recommended starting dose of POMALYST is 4 mg once daily orally on Days 1-21 of repeated 28-day cycles until disease progression. POMALYST may be given in combination with dexamethasone.
The side effects of this drug are NEUTROPENIA and THROBOCYTOPENIA.

If the toxicity with the drug is seen,then the therapy is started with dose of 3 mg ( one mg less than starting dose )

To initiate a new cycle of POMALYST, the neutrophil count must be at least 500 per mcL, the platelet count must be at least 50,000 per mcL. If toxicities occur after dose reductions to 1 mg, then discontinue POMALYST.
Discuss about this with your doctor.
I hope it helps
Thanks
I find this answer helpful

 1 user finds this helpful

1 Doctor agrees with this answer


Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now
Disclaimer: These answers are for your information only and not intended to replace your relationship with your treating physician.
This is a short, free answer. For a more detailed, immediate answer, try our premium service [Sample answer]
Share on
 

Related questions you may be interested in


Recent questions on Neutropenia


Loading Online Doctors....
Have Multiple Myeloma. Prescribed Pomalyst. Will Drop In Blood Levels?

Hello, POMALYST is indicated for patients with multiple myeloma who have received at least two prior therapies  and have demonstrated disease progression on or within 60 days of completion of the last therapy.  The recommended starting dose of POMALYST is 4 mg once daily orally on Days 1-21 of repeated 28-day cycles until disease progression. POMALYST may be given in combination with dexamethasone. The side effects of this drug are NEUTROPENIA and THROBOCYTOPENIA. If the toxicity with the drug is seen,then the therapy is started with dose of 3 mg ( one mg less than starting dose ) To initiate a new cycle of POMALYST, the neutrophil count must be at least 500 per mcL, the platelet count must be at least 50,000 per mcL. If toxicities occur after dose reductions to 1 mg, then discontinue POMALYST. Discuss about this with your doctor. I hope it helps Thanks