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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Have History Of Breast And Uterine Cancer. Ultrasound Showing Cyst On Left Ovary. Should I Be Tested For BRCA 1 And 2?

I have a strong history of breast and uterine cancer on my paternal side and would like to get genetic testing done but my PCM says I'm not at higher risk since its on my fathers side (my father died from colon cancer). I recently had an ultrasound done that showed a cyst on my left ovary but have been told that's normal. I am 53 years old, no menopause yet, never given birth. Should I be tested for BRCA 1 and 2? The paternal side: grandmother ovarian cancer and two aunts breast cancer all deceased.
Thu, 14 Nov 2013
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General Surgeon 's  Response
Hello madam , Thanks for full details u mentioned to evaluate the problem u had.
As ur paternal side grandmother and aunt suffered with breast cancer and ovarian cancer indicates they are ur second/third degree relatives. For BRCA 1 & BRCA 2 either maternal or paternal side ur are under high risk for inheriting the gene . Thus go for BRCA 1 & BRCA 2 testing. As u not attended menopause and u had no childs thus which increases ur general risk of developing cancer apart from gene defect . Thus i advice to go for yearly screening apart from BRCA gene screening.
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Have History Of Breast And Uterine Cancer. Ultrasound Showing Cyst On Left Ovary. Should I Be Tested For BRCA 1 And 2?

Hello madam , Thanks for full details u mentioned to evaluate the problem u had. As ur paternal side grandmother and aunt suffered with breast cancer and ovarian cancer indicates they are ur second/third degree relatives. For BRCA 1 & BRCA 2 either maternal or paternal side ur are under high risk for inheriting the gene . Thus go for BRCA 1 & BRCA 2 testing. As u not attended menopause and u had no childs thus which increases ur general risk of developing cancer apart from gene defect . Thus i advice to go for yearly screening apart from BRCA gene screening.