Hi there ~

I am sorry you are going through a lot with your depression. There is hope however since there is room to go up higher on Cymbalta to a 120 mg daily dosing in divided doses of 60 mg each in the AM and PM. Please try this for 2-3 weeks and you might see improvement. Vybrid is a new medicine of an older generation medicine that is useless almost, i.e. it is old wine in new bottle. I have not had much experience with it however it does make you drowsy and you need to be cautious. I would suggest that if the higher dose of cymbalta is not helping, you might want to switch to wellbutrin if you have not had a history of seizures in the past. Also try other things like psychotherapy, yoga, meditation, dhyana and daily physical exericise. They have proven evidence in treating depression in medical studies.

I hope this helps. Take care and have a lovely day !

Hi there, thanks for asking. I am happy that you have been doing well with Cymbalta for more than 6 months. It is not uncommon that a person who has been fine with Cymbalta 60 mg a day feels a little low again (Depression has an ebb tide nature). The dose could be easily increased to 120 mg a day by your doctor since 60 mg a day is the minimum dose for the treatment. Because you have been on 60 mg a day for several months its increasing will be tolerated by your system easily and the dose could be lowered even after one or two months. Meanwhile, it is one of the few medications which could help you in the aspect of weight (Vybrid cannot). Furthermore, Vybrid is from a different class of medications and it may not act as well as your current medication since every biology has its own characteristics and chemistry. It you are experiencing a stress factor in personal life or at work, it might be responsible for this change in the course of treatment. I hope you can manage it well if it is so and wish you the best health.