Hello, thanks for the query to H.C.M.
Answer as according to serial wise.
1. Typhoid fever
as you reported in your query is not positive because if >1:160 than it is +ve.
2. In G 6 P D , glucose
6 phosphate dehydrogenase helps in normal functioning of R B Cs so if there is deficiency than chances are of anemia
( may be acute or mostly chronic) so if you have anemia than above mentioned drugs are responsible for lowering of heamoglobin level further .
If no anemia than need not to worry.
3. All above mentioned drugs causes loss of appetite, gastritis
, hyper acidity, nausea
, sore mouth ( mouth bitterness).
You have mentioned that there are swelling over feet , yes, that's may be due to anemia or also may be due to hypo proteinaemia , so please assess these condition by examination of blood and urine analysis.
4. Since you have not typhoid fever so , where is the question of treatment.