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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Feeling Weak, Nausea, Mouth Bitterness, Loss Of Appetite And Swollen Foot. Given Artemeter, Lumefantrine. G6PD Patient? Medicines Safe? Treatment?

HELLO DOCTOR,
I AM 54 & 5 FEET 8 INCHES HEIGHT WITH G6PD FULL DEFECT. MY TYPHOID TEST RESULT WAS 1/80 1/80.
QUESTION 1. IS IT POSITIVE?
QUESTION 2. I WAS GIVEN ARTEMETER, LUMEFANTRINE, TETRACYCLINE & PARACETAMOL. AFTER THE COURSE I STILL FEEL WEAK, NAUSEA, MOUTH BITTERNESS, LOSS OF APPETITE AND A SWOLLEN FOOT. ARE THE DRUGS SAFE FOR G6PD PATIENTS?
QUESTION 3 WHAT CAN BE HAPPENING TO ME?
QUESTION 4 WHAT MEDICATIONS ARE SAFE FOR THE TREATMENT OF TYPHOID IN G6PD PATIENTS? FROM GODWIN.
Thu, 25 Apr 2013
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General & Family Physician,  's  Response
Hello, thanks for the query to H.C.M.
Answer as according to serial wise.
1. Typhoid fever as you reported in your query is not positive because if >1:160 than it is +ve.
2. In G 6 P D , glucose 6 phosphate dehydrogenase helps in normal functioning of R B Cs so if there is deficiency than chances are of anemia ( may be acute or mostly chronic) so if you have anemia than above mentioned drugs are responsible for lowering of heamoglobin level further .
i
If no anemia than need not to worry.
3. All above mentioned drugs causes loss of appetite, gastritis , hyper acidity, nausea, sore mouth ( mouth bitterness).
You have mentioned that there are swelling over feet , yes, that's may be due to anemia or also may be due to hypo proteinaemia , so please assess these condition by examination of blood and urine analysis.
4. Since you have not typhoid fever so , where is the question of treatment.
Regards.Dr. HET
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Feeling Weak, Nausea, Mouth Bitterness, Loss Of Appetite And Swollen Foot. Given Artemeter, Lumefantrine. G6PD Patient? Medicines Safe? Treatment?

Hello, thanks for the query to H.C.M. Answer as according to serial wise. 1. Typhoid fever as you reported in your query is not positive because if 1:160 than it is +ve. 2. In G 6 P D , glucose 6 phosphate dehydrogenase helps in normal functioning of R B Cs so if there is deficiency than chances are of anemia ( may be acute or mostly chronic) so if you have anemia than above mentioned drugs are responsible for lowering of heamoglobin level further . i If no anemia than need not to worry. 3. All above mentioned drugs causes loss of appetite, gastritis , hyper acidity, nausea, sore mouth ( mouth bitterness). You have mentioned that there are swelling over feet , yes, that s may be due to anemia or also may be due to hypo proteinaemia , so please assess these condition by examination of blood and urine analysis. 4. Since you have not typhoid fever so , where is the question of treatment. Regards.Dr. HET