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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Epilepsy. Suggested Encorate Chrono. Is It Sufficient?

After first attack of epilepsy , I have been suggested to take encorate chrono 500 mg twice a day. As suggested, I have taken the said dose of medicine for the last one year. Now please suggest to me whether I can reduce the dosage from 500 mg to 200 mg twice a day. My present age is 64 (female) and I have no previous family history of epilepsy. Please send the answer to the following email address: YYYY@YYYY
Wed, 20 Feb 2013
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Psychiatrist 's  Response
Hello kottapa******
Thanks for your question

Encorate chrono contains Sodium Valporate and its a broad spectrum anti epileptic drug that is it can be used in different type of seizures.
There has been debate whether to start Anti Epileptic Drugs even after single episode, but most of doctors prefer to start the therapy to remain on safer side so you are taking right medicine and right prescription.
Dose prescribed is also sufficient dose that is 1000 mg per day.
It has been a year and there is no episode so far, present guidelines advocate to continue drugs for at least 3 years without episodes. So as per my opinion you should not think to stop the drug or to decrease the dose (against the advise), as there is risk of rebound seizure activity.
Encorate chrono is a safe drugs and there are no major serious side effects of this drug, usually Nausea, vomiting, reversible alopecia, weight gain may be seen but they are tolerated easily.
So please don't think to reduce the dose.
thanks
take care
kindly rate
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Epilepsy. Suggested Encorate Chrono. Is It Sufficient?

Hello kottapa****** Thanks for your question Encorate chrono contains Sodium Valporate and its a broad spectrum anti epileptic drug that is it can be used in different type of seizures. There has been debate whether to start Anti Epileptic Drugs even after single episode, but most of doctors prefer to start the therapy to remain on safer side so you are taking right medicine and right prescription. Dose prescribed is also sufficient dose that is 1000 mg per day. It has been a year and there is no episode so far, present guidelines advocate to continue drugs for at least 3 years without episodes. So as per my opinion you should not think to stop the drug or to decrease the dose (against the advise), as there is risk of rebound seizure activity. Encorate chrono is a safe drugs and there are no major serious side effects of this drug, usually Nausea, vomiting, reversible alopecia, weight gain may be seen but they are tolerated easily. So please don t think to reduce the dose. thanks take care kindly rate