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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Elevated SGPT. Means To Lower It?

my sgpt is 158, can you please help me how to lower this, i m not alcholic so i m confused why it is elevated, and most of my lab results are normal and only the sgpt i m worried...and a few months ago my sgpt is only 47 and now it s 158, and i m also confused why my sgpt have different results than the other laboratory where i got 158.
Sat, 11 Aug 2012
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Gastroenterologist 's  Response
Hello,davetest59,
Causes of elevated SGPT enzyme are many. If all other liver tests are
normal, including Alkaline Phosphatase, Bilirubin, LDH,SGOT, then we
have to think about some medications or some supplements that you
may be taking. Overweight people also tend to have elevated enzymes
due to fatty changes in the liver. But we see elevation of all enzymes
to a certain extent. I have seen elevated SGPT in some that use
Protein powder for body building .I am also assuming that you have
had a complete Hepatitis-B and Hepatitis-C tests to rule these out.
Taking 800 units. of Vitamin-E once a day along with a 1000 mg. of
Vitamin-C would be helpful. Also Brewer's yeast tablet 1-2 a day.
Good luck.
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General & Family Physician Dr. Pavan Kumar Gupta's  Response
Hello
Elevated levels of SGPT are due to some liver injury.
The most common causes for non alcoholic reasons are various types of hepatitis,obesity,diabetes,use of certain medicines like anti seizures and anti biotics etc.
If these causes are ruled out then you should be investigated for other causes like wilson's disease,hemochromatosis,ulcerative colitis,Coeliac disease,crohn's disease etc.
It will be best for you if you consult a Gastroenterologist and get all the possible investigations done to find the exact cause.
The treatment will be decided on finding the cause.
Thanks
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Elevated SGPT. Means To Lower It?

Hello,davetest59, Causes of elevated SGPT enzyme are many. If all other liver tests are normal, including Alkaline Phosphatase, Bilirubin, LDH,SGOT, then we have to think about some medications or some supplements that you may be taking. Overweight people also tend to have elevated enzymes due to fatty changes in the liver. But we see elevation of all enzymes to a certain extent. I have seen elevated SGPT in some that use Protein powder for body building .I am also assuming that you have had a complete Hepatitis-B and Hepatitis-C tests to rule these out. Taking 800 units. of Vitamin-E once a day along with a 1000 mg. of Vitamin-C would be helpful. Also Brewer s yeast tablet 1-2 a day. Good luck.