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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Developed Severe Fatigue, Joint And Throat Pain, Tongue Swelling, Vaginal Sores On Taking Doxycycline. Allergic Reaction?

I took Doxycycline 100mg twice a day for a week and a half for acne . I developed severe fatigue , pain in joints, pain in throat, swelling of my tongue and sores around body including vagina. I stopped taking the medication on 11/16/12, but i still am feeling fatigue and the sores are still there, but they are healing. I went to the urgent care, they sent me to the er, er said there is nothing to be done, contact pcp, but my pcp does not have an opening for 3 and a half months. Did I have an allergic reaction to the doxycycline? I still feel very tired, what should I do?
Thu, 6 Dec 2012
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Emergency Medicine Specialist 's  Response
Hello and welcome to Healthcare Magic.

From the nature and sudden onset of your symptoms after taking Doxycycline, it is possible that they could be indicative of an allergic reaction. Since you have stopped the medication and your symptoms are subsiding, you don't have to worry much. It may sometimes take a few days for your symptoms like tiredness and fatigue to completely settle down. I would advise you to take plenty of fluids and eat a healthy, nutritious diet. If your symptoms remain persistent or worsen, then I would advise you to see a doctor for further evaluation, since certain conditions like anaemia or vitamin deficiencies can cause persistent fatigue.

Best wishes,
Dr. Sheeba Stephen
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Developed Severe Fatigue, Joint And Throat Pain, Tongue Swelling, Vaginal Sores On Taking Doxycycline. Allergic Reaction?

Hello and welcome to Healthcare Magic. From the nature and sudden onset of your symptoms after taking Doxycycline, it is possible that they could be indicative of an allergic reaction. Since you have stopped the medication and your symptoms are subsiding, you don t have to worry much. It may sometimes take a few days for your symptoms like tiredness and fatigue to completely settle down. I would advise you to take plenty of fluids and eat a healthy, nutritious diet. If your symptoms remain persistent or worsen, then I would advise you to see a doctor for further evaluation, since certain conditions like anaemia or vitamin deficiencies can cause persistent fatigue. Best wishes, Dr. Sheeba Stephen