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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Penicillin Cause Heartburn With Esophagus Burning Sensations?

Hi, I started taking Penicillen 500mg 2x/day for strep (also had thrown up & diarrhea simultaneously at onset of strep). I have been getting severe heartburn...burning in my esaphogus since I started. Its hard to eat & can be very painful. Is this a normal side effect? I plan to start Prilosec tomorrow.
Wed, 24 Sep 2014
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General Surgeon 's  Response
Hi.
Start Prilosec immediately.
I would advise the following in such a patient:
Continue Zantac 12 hourly.
Pepcid every 3 to 4 hours when on empty stomach.
Add Domperidone or such motility regulators.
Soft bland diet.
No aerated colas / soda/ drinks.
Early dinner. No late nights.
Treatment for anxiety (as prescribed / needs a prescription by your Doctor)
Lying in a reclining position
Walk around after dinner.
Think of the factors which increased the present problem, GERD, anxiety and try to avoid.
If no relief, get Upper GI endoscopy done and get prescription for added Medicines.
EKG for the heart n a safer side to rule out cardiac problems.
This helps all my patients and should help you hopefully.

IT is very rare for Penicillin to cause such a problem, not heard of really, but who knows ? So stop penicillin. You may be started on Intravenous or intramuscular antibiotics and anti-inflammatory like Diclofenac.
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Can Penicillin Cause Heartburn With Esophagus Burning Sensations?

Hi. Start Prilosec immediately. I would advise the following in such a patient: Continue Zantac 12 hourly. Pepcid every 3 to 4 hours when on empty stomach. Add Domperidone or such motility regulators. Soft bland diet. No aerated colas / soda/ drinks. Early dinner. No late nights. Treatment for anxiety (as prescribed / needs a prescription by your Doctor) Lying in a reclining position Walk around after dinner. Think of the factors which increased the present problem, GERD, anxiety and try to avoid. If no relief, get Upper GI endoscopy done and get prescription for added Medicines. EKG for the heart n a safer side to rule out cardiac problems. This helps all my patients and should help you hopefully. IT is very rare for Penicillin to cause such a problem, not heard of really, but who knows ? So stop penicillin. You may be started on Intravenous or intramuscular antibiotics and anti-inflammatory like Diclofenac.