The medication which is changed is for the glucoma, which is an eye condition in which the pressure inside eye increases which make it painful. The purpose of medication in glucoma is to decrease the pressure inside the eye. The 2 medication which you mentioned, both are used for the glucoma and depending on the severity more than one medication can also be used. If your wife is respoding to any of this medication in a better way than I would suggest you to continue with that medication and if she is not responding properly, than consult your doctor again.
Apart from that continue the medication which was prescibed for the tuberculoma
and abnormal blood glucose
Thanks and take care.