Hello, thanks for using health care magic. Masturbation has not been shown to have effect on the body. However, during masturbation it is possible to sustained traumatic lesions of the urethra or develop urethritis. Masturbation is in a bit to satisfy the sexual urge which is a normal feeling after puberty. The problem is becoming addicted because your psychosocial mind set will not be the same again. Severe addiction can lead to frequent stay in bed rooms, frequent touching of genitals consciously or unconsciously and even in public and reduce sexual response to opposite sex. Yes it can alter your mind set in your sexual life with your wife if you are severely addicted. A good way of cutting this would be by getting a partner or getting yourself busy, avoiding being lonely and avoiding pornographic and or romantic films. However, a strong will is required. Best regards and hope this helps you. Dr Achuo A. M.