Hello! After going through a detailed review of your discussion, I would like to comment on the condition --
1) The significantly raised liver
function parameters in a 30 weeks pregnancy
suggest a poor & grave outcome.
2) However, I would like to suggest you to hospitalize the patient immediately to have a multidisciplinary management. She requires to be observed by a 'team' of specialists containing an eminent gynecologist, a gastroenterologist, a general physician, an oncologist
& an intensive care expert.
3) The 'Itching' associated with a significant rise in the hepatic functional parameters is generally considered to be a manifestation of 'Obstructive Jaundice', which is many times a potentially lethal condition & may be associated with or a symptom of malignancy & may require surgery, but in this case seems to be a very complicated situation to manage.
Thanks & wishing a good recovery of your wife!