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What Is The Effect Of HLA B27 On The Teeth?

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Posted on Mon, 23 Feb 2015
Question: Does being hla b27+ affect your teeth in any way? YYYY@YYYY
doctor
Answered by Dr. Naval Mendiratta (26 minutes later)
Brief Answer:
role of hla b 27

Detailed Answer:
Good evening

Thank you for writing on health care magic

Well hla b 27 as such is not known to cause any effect on the teeth. We haven't encountered any patient who has the teeth affected due to the gene positivity. It mainly affects your eyes, your gastrointestinal tract. At times the gene can be positive in certain conditions affecting the stomach and intestines which can have a adverse effect on the oral cavity.

Do let us know what sort of problems you are facing and if any other disease due to hla b27 you are having. Will be able to guide you better with the details

Regards
Dr naval
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Naval Mendiratta (11 hours later)
I was diagnosed in 2006 but didn't have many problems with it other than iritis. In the past three years I have gotten psoriatic arthritis and psoriasis. Mainly having lots of back pain from that and I am losing the cartilage from my spine. Some intestinal problems but not to bad. Iritis, I have approximately three to four attacks a year. It just seems that within the past year I have had several cavities. I hadn't had that problem before and was wondering if it could be related to the b27.
doctor
Answered by Dr. Naval Mendiratta (9 hours later)
Brief Answer:
Cause of Dental Caries

Detailed Answer:
Good evening

Well HLA B 27 itself does not cause any caries as such. But yes, the sort of symptoms you are having with ongoing inflammation due to Psoriatic Arthritis can affect the normal teeth structure. Any form of inflammation causes loss of calcium from the bones, leading to it s weakness. Psoriasis itself usually affects the nails but very rarely it can harm the teeth.

But considering, HLA B 27 +ve, repeated attacks of iritis with Psoriatic Arthritis, i would recommend you to take proper treatment. You need to increase the dose of Folitrax to 20 mg and if needed may be Biological theraphy as well( Etarnacept or Infliximab). Talk to your treating doctor.

Do let me know for more queries

Regards
Dr Naval
Note: For further information on diet changes to reduce allergy symptoms or to boost your immunity, Ask here.

Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Naval Mendiratta

Rheumatologist

Practicing since :2007

Answered : 754 Questions

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What Is The Effect Of HLA B27 On The Teeth?

Brief Answer: role of hla b 27 Detailed Answer: Good evening Thank you for writing on health care magic Well hla b 27 as such is not known to cause any effect on the teeth. We haven't encountered any patient who has the teeth affected due to the gene positivity. It mainly affects your eyes, your gastrointestinal tract. At times the gene can be positive in certain conditions affecting the stomach and intestines which can have a adverse effect on the oral cavity. Do let us know what sort of problems you are facing and if any other disease due to hla b27 you are having. Will be able to guide you better with the details Regards Dr naval