Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
What Does The Survival Rate In A Hypereosinophilic Syndrome Patient Depend On?
Question: Mother has been diagnosed with HES ( hypereosinophillic syndrome). Her wbc today was 23.6. In your opinion, what is her prognosis? Her symptoms range from hypertention, itching, , cough, shortness of breath, mouth sours, muscle weakness, loose bowels. Her eosinophils have been elevated extremely for more than 6 months. She is 86 years old. Presently, she is being stepped down from prednisone for treatment of ITP. 40mg for a week. From what ive read, HES has no cure, how long in your opinion does she have to live, and what can i expect?
Brief Answer:
Prognosis and management of HES
Detailed Answer:
Hello,
Thank you for trusting HealthcareMagic
The survival rate of Hypereosinophilic syndrome is 80% survival at 5 years and a 42% survival at 15 years, which means that 80% and 42% people affected survive after 5 and 15 years respectively.
The prognosis greatly depends on the response to treatment, gene mutation associated, blast/leukemic changes and the extent to which other organs like heart gets affected.
First-line treatment is with glucocorticoids, followed by interferon, Imatinib, and chemotherapeutic agents.In nonresponsive cases stem cell transplantation can also be tried.
She would also need regular follow-up to monitor heart function and pulmonary function.
Please be advised to follow up with a Hematologist for further evaluation and management.
Hope this answers your question
Please feel free to address further questions here
Regards
Dr.Lekshmi
Prognosis and management of HES
Detailed Answer:
Hello,
Thank you for trusting HealthcareMagic
The survival rate of Hypereosinophilic syndrome is 80% survival at 5 years and a 42% survival at 15 years, which means that 80% and 42% people affected survive after 5 and 15 years respectively.
The prognosis greatly depends on the response to treatment, gene mutation associated, blast/leukemic changes and the extent to which other organs like heart gets affected.
First-line treatment is with glucocorticoids, followed by interferon, Imatinib, and chemotherapeutic agents.In nonresponsive cases stem cell transplantation can also be tried.
She would also need regular follow-up to monitor heart function and pulmonary function.
Please be advised to follow up with a Hematologist for further evaluation and management.
Hope this answers your question
Please feel free to address further questions here
Regards
Dr.Lekshmi
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now
Above answer was peer-reviewed by :
Dr. Arnab Banerjee
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
