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What Does The Following Thyroid Profile Result Indicate?

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Posted on Tue, 29 Sep 2015
Question: Hi,
I have been having problems with fatigue, major weight gain, clinical depression, insomnia, muscle aches, brittle nails and hair

a recent bloodtest showed TPO Ab as high at 424.00 (scale was 0.00-35.00 IU/ml). T4, TSH, Free T3 were all within normal range. Could this indicate Hashimoto's?
doctor
Answered by Dr. Binu Parameswaran Pillai (43 minutes later)
Brief Answer:
Hashimoto's thyroiditis

Detailed Answer:
Good day,
Noted your concern.
The elevated Anti TPO antibody suggests that you have Hashimoto's thyroiditis. Your Free T4 and TSH are normal now. However, there is a future risk of hypothyroidism since Anti TPO is elevated. You may also develop slight neck swelling due to thyroiditis.
Currently you do not require any medicines. However, there is some evidence that, selenium ( a mineral) can reduce anti TPO levels. You could try that for few months. May I suggest you to get the Free T4 and TSH repeated after 3 months.
Regards
Binu
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Binu Parameswaran Pillai (27 minutes later)
Thank you for your reply.
Is there a reason to see an endocrinologist at this time?
Also -- how is a definite diagnosis made?

many thanks
doctor
Answered by Dr. Binu Parameswaran Pillai (2 hours later)
Brief Answer:
No need to visit an endocrinologist unless you have a thyroid swelling

Detailed Answer:
Hi,
There is no point to meet an endocrinologist now. No intervention can change the natura course of hashimoto's thyroditis. However, there are some reports that, taking selenium can help to reduce Anti TPO levels.

please get a thyroid function test after 3 months and if the TSH start to rise above normal, please meet an endocrinologist. A defenite diagnosis is already made based on the high Anti TPO levels. If you have a thyroid swelling, an ultrasound scan should be done.There are no further tests required at this stage.
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Binu Parameswaran Pillai

Endocrinologist

Practicing since :2003

Answered : 1439 Questions

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What Does The Following Thyroid Profile Result Indicate?

Brief Answer: Hashimoto's thyroiditis Detailed Answer: Good day, Noted your concern. The elevated Anti TPO antibody suggests that you have Hashimoto's thyroiditis. Your Free T4 and TSH are normal now. However, there is a future risk of hypothyroidism since Anti TPO is elevated. You may also develop slight neck swelling due to thyroiditis. Currently you do not require any medicines. However, there is some evidence that, selenium ( a mineral) can reduce anti TPO levels. You could try that for few months. May I suggest you to get the Free T4 and TSH repeated after 3 months. Regards Binu