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What Does The Following Liver Test Report Indicate?

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Posted on Mon, 14 Aug 2017
Question: Hello doctor I recently went for my full body checkup and the reports for liver indicates following values
SGPT 105 AND SGOT 53. URIC ACID 7.5. Please advise medication for the same if required. I am taking fabustat 40 for uric acid
doctor
Answered by Dr. Ramesh Kumar (13 hours later)
Brief Answer:
elevation only more then three times the upper normal are significant.

Detailed Answer:
Hi,
As far as your liver enzymes are concerned -
Only elevation of SGOT and SGPT more then 3 times the upper normal value is clinically significant.Normally these enzymes are produced by liver cells.Liver cells being permeable allows these enzymes to diffuse into blood.Mild elevation of these enzymes have no significance.It should be at least 3 times more then normal for having any significance clinically.
As per general of hepatology-"Typically the range for normal AST is reported between 10 to 40 units per liter and ALT between 7 to 56 units per liter. Mild elevations are generally considered to be 2-3 times higher than the normal range".
So there is nothing clinically significant in reports.
Clinically if you are asymptomatic you are normal.
Suggestion-
Take
Legoglan once daily -It contain's sylimarin(milk of thistle) one of the most potent liver rejenuvator available in market.
As per NCBI-In liver diseases caused by oxidative stress drug- and chemical-induced hepatic toxicity), the antioxidant medicines such as silymarin can have beneficial effect. The silymarin exerts membrane-stabilizing and antioxidant activity, it promotes hepatocyte regeneration; furthermore it reduces the inflammatory reaction, and inhibits the fibrogenesis in the liver. These results have been established by experimental and clinical trials.

2)-Tocovid™ SupraBio™ is a natural combination of Tocotrienols (T3), Tocopherol, Phytosterols, Squalene and Mixed Carotenoids they are all high quality anti oxidant and prevent liver from any oxidative stress or injury by free radicals.An imbalance between too much oxidative stress and too little antioxidative defence has been suggested to cause a variety of liver diseases. Therefore, antioxidant supplements (beta carotene, and selenium) could have a potential role in patients with liver problems.

For uric acid continue same treatment.

Suggestion
Repeat liver function test every month.

Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
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Follow up: Dr. Ramesh Kumar (5 hours later)
Hello Doctor,

I forget to mention that i don't have gall bladder as it was removed around 10 years back due to stones in it. Please advise medication after considering the same, sorry for not mentioning on the first time. Thank you
doctor
Answered by Dr. Ramesh Kumar (3 minutes later)
Brief Answer:
Follow up.

Detailed Answer:
Hi dear,
No problems if you don't have gall bladder.Role of gallbladder is just to store bile.

Medications are-
Legoglan once daily.
Tocovid™ SupraBio™ once daily
Liv 52 double srenght once daily
To be taken with breakfast 9 a.m
Take them for 1 month and repeat LFT.
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Kampana
doctor
Answered by
Dr.
Dr. Ramesh Kumar

Gastroenterologist

Practicing since :1986

Answered : 2906 Questions

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What Does The Following Liver Test Report Indicate?

Brief Answer: elevation only more then three times the upper normal are significant. Detailed Answer: Hi, As far as your liver enzymes are concerned - Only elevation of SGOT and SGPT more then 3 times the upper normal value is clinically significant.Normally these enzymes are produced by liver cells.Liver cells being permeable allows these enzymes to diffuse into blood.Mild elevation of these enzymes have no significance.It should be at least 3 times more then normal for having any significance clinically. As per general of hepatology-"Typically the range for normal AST is reported between 10 to 40 units per liter and ALT between 7 to 56 units per liter. Mild elevations are generally considered to be 2-3 times higher than the normal range". So there is nothing clinically significant in reports. Clinically if you are asymptomatic you are normal. Suggestion- Take Legoglan once daily -It contain's sylimarin(milk of thistle) one of the most potent liver rejenuvator available in market. As per NCBI-In liver diseases caused by oxidative stress drug- and chemical-induced hepatic toxicity), the antioxidant medicines such as silymarin can have beneficial effect. The silymarin exerts membrane-stabilizing and antioxidant activity, it promotes hepatocyte regeneration; furthermore it reduces the inflammatory reaction, and inhibits the fibrogenesis in the liver. These results have been established by experimental and clinical trials. 2)-Tocovid™ SupraBio™ is a natural combination of Tocotrienols (T3), Tocopherol, Phytosterols, Squalene and Mixed Carotenoids they are all high quality anti oxidant and prevent liver from any oxidative stress or injury by free radicals.An imbalance between too much oxidative stress and too little antioxidative defence has been suggested to cause a variety of liver diseases. Therefore, antioxidant supplements (beta carotene, and selenium) could have a potential role in patients with liver problems. For uric acid continue same treatment. Suggestion Repeat liver function test every month.