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What Do My Blood Test Reports Indicate?

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Posted on Wed, 31 Dec 2014
Question: I have chronic acidity and gastritis problems for last 15 years. I am suffering from jaundice which was detected in 2002 when I was hospitalized for enteric fever. My bilirubin was as high as2.0. No treatment could lower it. But liver function test was normal except high bilirubin. In 2005 a doctor told me that I had XXXXXXX syndrome. I didn't consult other doctors from then. In April 2014 I fell ill and LFT result showed that both bilirubin and sgpt was high. Blood pressure was 110/70. Sgpt= 82, bilirubin=11.2. After four months medication bilirubin was 3.75 and sgpt=24. In November when I did a routine check it was found that my bilirubin=5.2and sgpt=93. Now my sgpt=48 and bilirubin 4.73. My doctor suggest some blood tests which results as follows: pt=13.1, prothrombin index=85.5, isi=0.98, inr=1.17, bilirubin=5.3, conjugated=0.7, unconjgated=4.6, total protein =8.2, albumin=5.5, globulin=2.7, ag ratio=2.1, serum alkaline phosphate=9.6, sgot=33, sgpt=48,
Hb=10.6, rbc=5.27millions/cumm, mcv=64.9fl, mch=20.1pg, rdw=16.1%, hbf=2.0%, hba2+e=80.5%.
I am a male, aged=35.
doctor
Answered by Dr. Monish De (17 minutes later)
Brief Answer:
You are suffering from familial nonhemolytic jaundice.

Detailed Answer:
Hi

Your blood test suggest you are suffering from Gilbert's syndrome.

It is a common, mild liver condition in which the liver doesn't properly process a substance called bilirubin.

Bilirubin is produced by the breakdown of red blood cells.

It is caused by an inherited gene mutation.

It is also known as constitutional hepatic dysfunction and familial nonhemolytic jaundice.

It is caused by an abnormal gene that you inherit from your parents.

The gene controls an enzyme that helps break down bilirubin in your liver.

With an ineffective gene, excess amounts of bilirubin build up in your blood.

The combination of normal blood and liver function tests and elevated bilirubin levels is an indicator of Gilbert's syndrome.

The disease does not require treatment.

The bilirubin levels in your blood may fluctuate over time and you may occasionally experience jaundice. But this usually goes away on its own, and it doesn't cause any ill effects.

I will advise you to choose a healthy diet full of fruits and vegetables.

Avoid extremely low calorie diets. Stick to a routine eating schedule and avoid fasting or skipping meals.

You need to manage stress.

Find ways to deal with the stresses in your life. Consider exercise or quiet time alone to cope with stress.

Regards

DR DE
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Monish De (28 minutes later)
But a comment in the electrophoresis test is: Consistent with Haemoglobin E disease.
What it interprets?
doctor
Answered by Dr. Monish De (16 minutes later)
Brief Answer:
Ct scan of upper abdomen

Detailed Answer:
Hi

People with haemoglobin E disease have mild spleen enlargement and mild hemolytic anemia.

They do not suffer from high bilirubin.

Your latest blood report suggest bilirubin 5.3 which is high with normal SGOT and SGPT liver function test.

Normal red blood cell count is 4.7 to 6.1 million/mcL and in your case it is 5.27 which is normal and suggest you are not suffering from anaemia and rules out Haemoglobin E disease.

I will advise you to do a CT scan of upper abdomen to see if there is any spleen enlargement.

You are most probably suffering from Gilbert's syndrome which requires no treatment.

Regards

DR DE
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Monish De

Oncologist

Practicing since :2004

Answered : 2229 Questions

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What Do My Blood Test Reports Indicate?

Brief Answer: You are suffering from familial nonhemolytic jaundice. Detailed Answer: Hi Your blood test suggest you are suffering from Gilbert's syndrome. It is a common, mild liver condition in which the liver doesn't properly process a substance called bilirubin. Bilirubin is produced by the breakdown of red blood cells. It is caused by an inherited gene mutation. It is also known as constitutional hepatic dysfunction and familial nonhemolytic jaundice. It is caused by an abnormal gene that you inherit from your parents. The gene controls an enzyme that helps break down bilirubin in your liver. With an ineffective gene, excess amounts of bilirubin build up in your blood. The combination of normal blood and liver function tests and elevated bilirubin levels is an indicator of Gilbert's syndrome. The disease does not require treatment. The bilirubin levels in your blood may fluctuate over time and you may occasionally experience jaundice. But this usually goes away on its own, and it doesn't cause any ill effects. I will advise you to choose a healthy diet full of fruits and vegetables. Avoid extremely low calorie diets. Stick to a routine eating schedule and avoid fasting or skipping meals. You need to manage stress. Find ways to deal with the stresses in your life. Consider exercise or quiet time alone to cope with stress. Regards DR DE