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What Do AST Level Of 39 And ALT Level Of 75 Indicate?

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Posted on Thu, 8 Jun 2017
Question: I just received my lab results which show AST of 39 and ALT of 75...my doctor advised me to take NAC. Will that be enough to lower the results, or should i look for a second opinion?
doctor
Answered by Dr. Sunil (54 minutes later)
Brief Answer:
Most likely age-related oxidative stress.

Detailed Answer:
Hello Dear,
Thank you for choosing HealthcareMagic for your query.
Have gone through your details, reviewed the attached reports and I appreciate your concerns.

Liver is an organ made up of a number of small units called cells. Whenever there is an injury or toxin induced damage in the liver the cells get inflamed and swell up.The membrane lining the cell becomes more permeable and hence the liver enzymes stored inside it moves out of the cell into the blood causing elevation of the liver enzyme.

To be clinically significant this rise in enzyme level should be minimum three times the normal. Your levels are just mildly deranged most likely due to oxidative age-related injury.

To treat the problem we have to initially rule out the cause.
Liver enzymes could be deranged because of a number of causes like Hepatitis, Cirrhosis or other pathologies. So unless we treat the cause of deranged Liver function we can't correct it.

In short, deranged liver functions are just a sign of liver injury. So treating the cause is essential to healing the liver again. However, as enzymes are not grossly deranged in your case we consider oxidative age-related stress as the primary cause of mildly deranged liver enzymes.

N-acetylcysteine (NAC) is frequently utilized where intracellular oxidant-antioxidant balance is concerned. Studies have proved that NAC has a protective effect against liver injury in humans.

However, initially, few more tests should be done like-
Ultrasound liver- To rule out liver pathology(To be on very safe side)

As of now start NAC.
Start taking silymarin(Potent liver rejuvenator).
Vitamin and antioxidant supplements would also help.

Right now no need for the secondary opinion.

Hope this helped. Follow ups are most welcome.
I wish you great health.
Thanks.
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
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Dr. Sunil

Gastroenterologist

Practicing since :1982

Answered : 351 Questions

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What Do AST Level Of 39 And ALT Level Of 75 Indicate?

Brief Answer: Most likely age-related oxidative stress. Detailed Answer: Hello Dear, Thank you for choosing HealthcareMagic for your query. Have gone through your details, reviewed the attached reports and I appreciate your concerns. Liver is an organ made up of a number of small units called cells. Whenever there is an injury or toxin induced damage in the liver the cells get inflamed and swell up.The membrane lining the cell becomes more permeable and hence the liver enzymes stored inside it moves out of the cell into the blood causing elevation of the liver enzyme. To be clinically significant this rise in enzyme level should be minimum three times the normal. Your levels are just mildly deranged most likely due to oxidative age-related injury. To treat the problem we have to initially rule out the cause. Liver enzymes could be deranged because of a number of causes like Hepatitis, Cirrhosis or other pathologies. So unless we treat the cause of deranged Liver function we can't correct it. In short, deranged liver functions are just a sign of liver injury. So treating the cause is essential to healing the liver again. However, as enzymes are not grossly deranged in your case we consider oxidative age-related stress as the primary cause of mildly deranged liver enzymes. N-acetylcysteine (NAC) is frequently utilized where intracellular oxidant-antioxidant balance is concerned. Studies have proved that NAC has a protective effect against liver injury in humans. However, initially, few more tests should be done like- Ultrasound liver- To rule out liver pathology(To be on very safe side) As of now start NAC. Start taking silymarin(Potent liver rejuvenator). Vitamin and antioxidant supplements would also help. Right now no need for the secondary opinion. Hope this helped. Follow ups are most welcome. I wish you great health. Thanks.