Brief Answer: Yes it may Detailed Answer: Hello, Thanks for choosing health care magic for posting your query. I have gone through your question in detail and I can understand what you are going through. Paroxetine is an antidepressant which has action on multple neuro transmitters. Being non selective the side effect potential is also very varied. Reduced capacity to sprint can be associated with paroxetine due to its effect on serotonin transmission. You may consider changing the anti depressant which can make you sure whether paroxetine was really affecting your sprint capacity or not. Another possibility is that you may be still having some depression and your reduced physical capacity couod be a manifestation of depression. So try changing the drug first and if not then your treating psychiatrist needs to treat the depression more intensively. Hope I am able to answer your concerns. If you have any further query, I would be glad to help you. If not, you may close the discussion and if possible you may rate the answer for me, so that I get a good feedback. In future if you wish to contact me directly, you can use the below mentioned link: bit.ly/dr-srikanth-reddy Wish you good health, Kind regards Dr. Srikanth Reddy M.D.

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