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What Causes Pitting Edema Of Left Foot And Ankle When On Amlodipine?

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Posted on Mon, 14 Apr 2014
Question: Hello Dr. I am a 74 y.o. female - active and healthy. Approx., one year ago I developed hypertension and it has been controlled well with Amlodipine 7.5 mg. Take cylexia for Fibromyalgia, and have mild asthma - no prob. unless I develop a cold. Current Problem. about 3 weeks ago - I suddenly developed pitting edema of left foot and ankle only. no pain- no limitation in movement or walking. no edema of rt. foot is noted.
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Answered by Dr. Lohit K (1 hour later)
Brief Answer: amlodepine may cause? organ system or local proble Detailed Answer: Hi, thanks for using HCM. I went through the query and understood your concern. Since there is no limitations of movement, no pain or tenderness and no signs of inflammation, the probable cause for pitting edema at ankle and knee joint may be amlodepine. This drug has been known to cause edema. So with your doctor's advice you can reduce the dose to 5mg with monitoring BP and can shift to other drugs like telmisartan or losartan (ARB) which ore devoid of this side effect. The other causes for this problem may be any injury or infection in limb or other any organ system problem like liver, kidney or anaemia. You can get done blood test to ruleout these problem. I hope this information helps you. Feel free to ask if any further queries and I will be glad to answer them. Wish you good health and faster recovery. Regards
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Lohit K

General & Family Physician

Practicing since :2007

Answered : 1648 Questions

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What Causes Pitting Edema Of Left Foot And Ankle When On Amlodipine?

Brief Answer: amlodepine may cause? organ system or local proble Detailed Answer: Hi, thanks for using HCM. I went through the query and understood your concern. Since there is no limitations of movement, no pain or tenderness and no signs of inflammation, the probable cause for pitting edema at ankle and knee joint may be amlodepine. This drug has been known to cause edema. So with your doctor's advice you can reduce the dose to 5mg with monitoring BP and can shift to other drugs like telmisartan or losartan (ARB) which ore devoid of this side effect. The other causes for this problem may be any injury or infection in limb or other any organ system problem like liver, kidney or anaemia. You can get done blood test to ruleout these problem. I hope this information helps you. Feel free to ask if any further queries and I will be glad to answer them. Wish you good health and faster recovery. Regards