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What Causes Inflammation Around Cancer Tissues?
Question: Academic question.
If there is inhibition of T cell activation in cancer how do you explain why there is often inflammation in the surrounding tissues, eg esophageal cancer.
If there is inhibition of T cell activation in cancer how do you explain why there is often inflammation in the surrounding tissues, eg esophageal cancer.
Brief Answer:
There are many pathways going on
Detailed Answer:
Hi
Thanks for your query.
In tumor microenvironment there are many cells and pathways going on. On one hand there are Treg cells which inhibit immunity/inflammation. On another hand are proinflammatory cells and helper T cells. The balance determines the level of inflammation and prognosis.
In general, infiltrating tumor lymphocytes are dissociated with better prognosis in cancer.
Regards
There are many pathways going on
Detailed Answer:
Hi
Thanks for your query.
In tumor microenvironment there are many cells and pathways going on. On one hand there are Treg cells which inhibit immunity/inflammation. On another hand are proinflammatory cells and helper T cells. The balance determines the level of inflammation and prognosis.
In general, infiltrating tumor lymphocytes are dissociated with better prognosis in cancer.
Regards
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Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Answered by
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