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What Causes Elevated Liver Enzymes?

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Posted on Wed, 23 Sep 2015
Question: I am 30 and have elevated liver enzymes (AST 90, ALT 220, Albumin 5.5). A CT Scan shows fatty infiltration on my liver. I am overweight, but do not drink, and I have no symptoms. Do my liver tests indicate possible cirrhosis?
doctor
Answered by Dr. Dr.P.Ratnakar Kini (2 hours later)
Brief Answer:
Fatty liver only. No cirrhosis.

Detailed Answer:
Hi,
Thanks for posting your query.
I am Dr.R.K and I am pleased to assist you.
Your liver enzymes are significantly raised.
ALT is increased more than AST.
Though there are many different causes for this raise the most common cause is fatty liver and it has been confirmed by the CT scan. The scan has not shown any features suggestive of cirrhosis.
So you do not have cirrhosis.
You need to do undergo few tests like HBsAg, antiHCV, serum ceruloplasmin, ANA, AMA,ASMA and AntiLKM to rule out other common causes which can raise liver enzymes.
Blood glucose and lipid profile should also be done as raised levels can cause fatty liver.
As far as treatment is concerned, weight reduction is the first step.
You can take trimethyl glycine supplements.
I hope that answers your query.
Let me know if you have any more questions.
Regards,
Dr.R.K
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr.P.Ratnakar Kini (3 hours later)
Thank you. I have had multiple blood tests, including those you mentioned, and there were no apparent issues. My doctor has ordered a biopsy. About how long does it usually take to reverse NAFLD through diet and exercise?
doctor
Answered by Dr. Dr.P.Ratnakar Kini (20 hours later)
Brief Answer:
3-6 months after the risk factor is eliminated.

Detailed Answer:
Hi,
Weight reduction is the first step.
It may take 3-6 months to reverse it after all the risk factors are treated.

Regards,
Dr.R.K.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr.P.Ratnakar Kini

Gastroenterologist

Practicing since :1994

Answered : 2215 Questions

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What Causes Elevated Liver Enzymes?

Brief Answer: Fatty liver only. No cirrhosis. Detailed Answer: Hi, Thanks for posting your query. I am Dr.R.K and I am pleased to assist you. Your liver enzymes are significantly raised. ALT is increased more than AST. Though there are many different causes for this raise the most common cause is fatty liver and it has been confirmed by the CT scan. The scan has not shown any features suggestive of cirrhosis. So you do not have cirrhosis. You need to do undergo few tests like HBsAg, antiHCV, serum ceruloplasmin, ANA, AMA,ASMA and AntiLKM to rule out other common causes which can raise liver enzymes. Blood glucose and lipid profile should also be done as raised levels can cause fatty liver. As far as treatment is concerned, weight reduction is the first step. You can take trimethyl glycine supplements. I hope that answers your query. Let me know if you have any more questions. Regards, Dr.R.K