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Suggest Treatment For Depression, Tremors In Hands And Loss Of Appetite

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Posted on Mon, 2 Feb 2015
Question: After taking alprax 0.5 mg 20 to 30 tablets per day in divided doses from august 2012 to august 2014 (suffering from major depression) i myself go to pysychiatrist and was hospitalised on 1 september 2014 and after detoxification by oral and injectable medicines was discharged on 22 september 2014.I was prescribed toficalm 100 mg BD, ciplar 40 mg BD, paxidep12.5 mg BD and lamictal 25 mg BD but after three days due to lot of tremors in hand and loss of appetite lamictal was stopped.I am taking prescribed medicine till now but im still in depression.I m very hypo,feeling very difficulty in talking with others slowed movements, lethargic, difficulty in speaking with others on phone.I feel ok fwhenever i took zolpidem 10 mg with clonazepam 0.5 mg two tablets for one and half an hour feel very active feel energetic in talking with others then after one and half an hour again feel depressed inactive feel again lethargic slowed movements ! I feel very depressed when i am in hypo no interest in life.10 days back i myself started taking impiramine 75 mg morning 75 mg afternoon and 150 mg before night and was feeling ok and talkative. I WAS FEELING VERY POSITIVE but after7 days i was again in hypo state.Please suggest some medicine so that i remain all the day in normal or hyper condition. Whenever i took benzodiazepines i feel normal in my daily routine and very positive.Pls suggest some medicines other than benzos as benzodiazepines are wery dangerous for health and one of my frieng suggest me spasmo pyroxyvon Can i take this.I want to remain in hyper state throughout my rest of life because i feel positive and out of depression in hyper state.I m under lot of stress of large family business and death of my only elder brother in 2003
doctor
Answered by Dr. Seikhoo Bishnoi (42 minutes later)
Brief Answer:
The symptoms are due to protracted withdrawal of benzodiazepine

Detailed Answer:
Hello thanks for choosing HCM for your health related queries

I can understand your concern. You have been taking Alprazolam 0.5 mg tabs 20-30 tabs per day since Aug 2012 to Aug 2014. Then you decided to quit and took help from a psychiatrist. You were kept hospitalised and were discharged with Toficalm, Ciplar (Propranolol), Paxidep (Paroxetine) and Lamictal (Lamotrigine). Later lamotrigine stopped because of side effects.

Still you have persistent symptoms like lethargy, depressed mood, inactive feelings etc. These effects usually go by taking Zolpidem or Clonazepam. Since last 10 days you have started taking Imipramine and are feeling ok but you again developed hypo like state.

Now coming to management-

First of all as you have taken Alprazolam (a benzodiazepine) for about 2 years in high doses, so even after successful deaddiction for some months you may suffer feeling of lack of energy, lethargy, depressed mood because of long term withdrawal symptoms. The withdrawal is called as protracted withdrawal and as per my opinion some anticraving drug should be added to your therapy to reduce the symptoms. Medicines like Pregabalin, Baclofen can help you to reduce the symptoms in such case. There medicines will reduce restlessness and symptoms of episodic craving. I would strongly advise you to NOT to take ZOLPIDEM or any BENZODIAZEPINE drug again because this may make you dependent on medicines again.

Spasmo Proxyvon is an opioid medicine and taking the drug will not affect your symptoms because the drug have different actions that Benzodiazepines. But the drug is considered as narcotic substance and it has stronger abuse potential than Alprazolam. The drug will make you addicted and it is difficult to come out of its addictions. SO PLEASE DONT THINK TO TAKE THIS MEDICINE TO REDUCE YOUR SYMPTOMS.

Continue to take your prescribed medicines and discuss with your doctor regarding prescription of medicines I have mentioned and you will feel better.

Try to spend your time in constructive activities like playing outdoor games, listening music, doing your work properly.

Don't remain alone for long periods of time.

Exercise daily and you can attend behaviour therapy session to keep yourself relaxed. All these measures will increase your confidence and you will feel better.


Thanks, hope this helps you
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Seikhoo Bishnoi (29 hours later)
Im still suffering still from major depression and anxiety mental craving how much mg of pregabalin i should take or how much mg of baclofen i should take
doctor
Answered by Dr. Seikhoo Bishnoi (7 minutes later)
Brief Answer:
Consult your psychiatrist for prescription of the drugs.

Detailed Answer:
Hello again

Pregabalin 150 mg in two decided doses and Baclofen 30 mg in three decided doses should be able to reduce your anxiety and symptoms of craving. Continue to take you antidepressants as advised. Discuss with your psychiatrist for prescription of these drugs. Don't take benzodiazepines or zolpidem for your anxiety, this will make you dependent again.

Thanks, hope this helps you
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. Seikhoo Bishnoi

Psychiatrist

Practicing since :2007

Answered : 5193 Questions

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Suggest Treatment For Depression, Tremors In Hands And Loss Of Appetite

Brief Answer: The symptoms are due to protracted withdrawal of benzodiazepine Detailed Answer: Hello thanks for choosing HCM for your health related queries I can understand your concern. You have been taking Alprazolam 0.5 mg tabs 20-30 tabs per day since Aug 2012 to Aug 2014. Then you decided to quit and took help from a psychiatrist. You were kept hospitalised and were discharged with Toficalm, Ciplar (Propranolol), Paxidep (Paroxetine) and Lamictal (Lamotrigine). Later lamotrigine stopped because of side effects. Still you have persistent symptoms like lethargy, depressed mood, inactive feelings etc. These effects usually go by taking Zolpidem or Clonazepam. Since last 10 days you have started taking Imipramine and are feeling ok but you again developed hypo like state. Now coming to management- First of all as you have taken Alprazolam (a benzodiazepine) for about 2 years in high doses, so even after successful deaddiction for some months you may suffer feeling of lack of energy, lethargy, depressed mood because of long term withdrawal symptoms. The withdrawal is called as protracted withdrawal and as per my opinion some anticraving drug should be added to your therapy to reduce the symptoms. Medicines like Pregabalin, Baclofen can help you to reduce the symptoms in such case. There medicines will reduce restlessness and symptoms of episodic craving. I would strongly advise you to NOT to take ZOLPIDEM or any BENZODIAZEPINE drug again because this may make you dependent on medicines again. Spasmo Proxyvon is an opioid medicine and taking the drug will not affect your symptoms because the drug have different actions that Benzodiazepines. But the drug is considered as narcotic substance and it has stronger abuse potential than Alprazolam. The drug will make you addicted and it is difficult to come out of its addictions. SO PLEASE DONT THINK TO TAKE THIS MEDICINE TO REDUCE YOUR SYMPTOMS. Continue to take your prescribed medicines and discuss with your doctor regarding prescription of medicines I have mentioned and you will feel better. Try to spend your time in constructive activities like playing outdoor games, listening music, doing your work properly. Don't remain alone for long periods of time. Exercise daily and you can attend behaviour therapy session to keep yourself relaxed. All these measures will increase your confidence and you will feel better. Thanks, hope this helps you