Drug withdrawal is the group of symptoms that occur upon the abrupt discontinuation or decrease in intake of medications or recreational drugs.

In order to experience the symptoms of withdrawal, one must have first developed a physical or mental dependence. This happens after consuming one or more substances for a certain period of time, which is both dose dependent and varies based upon the drug consumed. For example, prolonged use of an anti-depressant is most likely to cause a much different reaction when discontinued than the repeated use of an opioid, such as heroin. Withdrawal symptoms from opiate abuse (such as heroin/morphine) include anxiety, sweating, vomiting, and diarrhea. Alcohol abuse withdrawal symptoms include irritability, fatigue, shaking, sweating, and nausea. Withdrawal from nicotine brings on irritability, fatigue, insomnia, headache, and difficulty concentrating. Symptoms and body response to the absence can vary from mild discomfort, or to the return of previous underlying medical problems and their respective symptoms. Many legal and unrestricted chemicals and/or substances available without prescriptions and over the counter can cause withdrawal effects when users stop consuming them, even if taken as directed.

The route of administration, whether intravenous, intramuscular, oral or otherwise, can also play a role in determining the severity of withdrawal symptoms. There are different stages of withdrawal as well; generally, a person will start to feel bad (crash or come down), progress to feeling worse, hit a plateau, and then the symptoms begin to dissipate. However, withdrawal from certain drugs (benzodiazepines, alcohol) can be fatal. While it is seldom fatal to the user, withdrawal from opiates (and some other drugs) can cause miscarriage, due to fetal withdrawal. The term "cold turkey" is used to describe the sudden cessation use of a substance and the ensuing physiologic manifestations.

The symptoms from withdrawal may be even more dramatic when the drug has masked prolonged malnutrition, disease, chronic pain, infections (common in intravenous drug used) or sleep deprivation, conditions that drug abusers often suffer as a secondary consequence of the drug. Many drugs (including alcohol) suppress appetite while simultaneously consuming any money that might have been spent on food. When the drug is removed, the discomforts return in force and are sometimes confused with addiction withdrawal symptoms.

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Withdrawal symptoms

What is Withdrawal symptoms?

Drug withdrawal is the group of symptoms that occur upon the abrupt discontinuation or decrease in intake of medications or recreational drugs.

In order to experience the symptoms of withdrawal, one must have first developed a physical or mental dependence. This happens after consuming one or more substances for a certain period of time, which is both dose dependent and varies based upon the drug consumed. For example, prolonged use of an anti-depressant is most likely to cause a much different reaction when discontinued than the repeated use of an opioid, such as heroin. Withdrawal symptoms from opiate abuse (such as heroin/morphine) include anxiety, sweating, vomiting, and diarrhea. Alcohol abuse withdrawal symptoms include irritability, fatigue, shaking, sweating, and nausea. Withdrawal from nicotine brings on irritability, fatigue, insomnia, headache, and difficulty concentrating. Symptoms and body response to the absence can vary from mild discomfort, or to the return of previous underlying medical problems and their respective symptoms. Many legal and unrestricted chemicals and/or substances available without prescriptions and over the counter can cause withdrawal effects when users stop consuming them, even if taken as directed.

The route of administration, whether intravenous, intramuscular, oral or otherwise, can also play a role in determining the severity of withdrawal symptoms. There are different stages of withdrawal as well; generally, a person will start to feel bad (crash or come down), progress to feeling worse, hit a plateau, and then the symptoms begin to dissipate. However, withdrawal from certain drugs (benzodiazepines, alcohol) can be fatal. While it is seldom fatal to the user, withdrawal from opiates (and some other drugs) can cause miscarriage, due to fetal withdrawal. The term "cold turkey" is used to describe the sudden cessation use of a substance and the ensuing physiologic manifestations.

The symptoms from withdrawal may be even more dramatic when the drug has masked prolonged malnutrition, disease, chronic pain, infections (common in intravenous drug used) or sleep deprivation, conditions that drug abusers often suffer as a secondary consequence of the drug. Many drugs (including alcohol) suppress appetite while simultaneously consuming any money that might have been spent on food. When the drug is removed, the discomforts return in force and are sometimes confused with addiction withdrawal symptoms.

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Questions and answers on "Withdrawal symptoms"

Morphine - I have been taking about 180mg of morphine a day the past year. Any suggestions on how to wean off? Cold turkey was a nightmare and I am not sure if I should tell my doctor cuz I was an abuser/buyer

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Hi,
Welcome to healthcare Magic!
Tell everything to your doctor, doctors have a boundation of professional secret so you can be sure no one will come to know about it.
Morphine causes physical dependence and causes severe withdrawal symptoms when withholding.
It should be done in the supervision...
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i am 25 and been addicted to herion since ive been 18. since i dont have the money or transportation to get suboxone i buy them off the streets. ive been clean for bout 2 months now. i still have minor withdrawal symptoms when i dont have them what do u recomend?
Hi,
Heroin is the most notorious of all substances and has the most intense cravings. I congratulate you for being clean for 2 months so far and hope you will continue the same. In absence of replacement therapy like suboxone, you can use symptomatic management like pain killers Diclofenac or...
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I grew up with parents who smoke heavily. When I left home for uni I had terrible withdrawal symptoms, mood swings, increased appetite loss of sleep etc etc (although I had never smoked). I had to buy some nicotine patches and that sorted the problem.... 6 years ago. Are there any long term health effects I should worry about?
Hi dear,
nicotine patches has nicotine itself so it has long term health effect and so i suggest you not to continue it for long time.
though it has very less health effect than actual smoking.
so not to start smoking.
there are many other medication which help you to overcome withdrawal like...
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i have chronic insomina now 3 1/2 years i hve a hole in nasal seputm and have been using cocaine now 30 years i had sleep study done results where insomina my insomina started after the perforation to my septum taking 100mg sequeriial and 30mg restiol and only get 4 hours of sleep what can i do or what do u adivise me to do stop using 0ne month now
Hi ....you have already have complication of cocaine ...you are having nasal hole which may be causing problem in sleeping for you....you need to visit a ENT specialist and ask for its treatment. As you have mentioned that you stopped cocaine one month back , I m sure you must not be having any...
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I was on methadone for approx 12 years. I have recently gone through a gradual detox of 1ml per day from when I got down to 10ml. I was successful in coming off the methadone but have been suffering minor withdrawal symptoms for the last 18 days. This has been going on while I have been on a course of Lofexidine, Ibuprofen, Paracetamol, and Prozac which I have taken for a number of years. I have tried to detox off the Lofexidine twice now, but each time my symptoms come back in a big way and I need to start taking Diazapam to calm me down and to help with my sleep pattern. Subsequently I keep needing to get my dose of Lofexidine put back up. I would like to know if it is okay to carry on with the Lofexidine treatment as I have been on it for 26 days now and although it seems to help with my symptoms, I Don't like it's side effects that it gives me. I would like to know what your opinion is of Lofexidine as part of my treatment, whether it would be a good idea to start taking any vitamins, etc, although I am eating quite well and drinking a lot of water. I am wondering how long I can keep this up for as I have read that withdrawal symptoms from methadone can last between 30 to 60 days.
Hi there ~

Although you do not mention what side effects of lofexidine you are having, it seems like they are bad enough to make you think of any other medication that will help with the withdrawals from methadone. I suggest that you consult you doctor who prescribed the lofexidine to find out if...
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I'm curious what the most common withdrawal symptoms are when/if I were to stop taking the Adderral my Dr. has prescribed me? Thank you for any input you can provide. It's easier to know what to expect than to start feeling strange & not knowing why.
Dear patient,

Thanks for your health concerns. Adderal is an amphetamine medication and thus stimulant of the nervous system; withdrawal symptoms are usually the opposite of those related to drug effect: irritability, somnolence, fatigue, depressed mood, changes in appetite, loss of energy and...
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Hi, I have recently come off a long course of antidepressants. Namely Lexapro , an SSRI. I am experiencing horrid withdrawal symptoms, similar to vertigo - dizzyness and bodyshock sensations. What can I take to ease these symptoms, and how long will the symptoms last? I was on Lexapro for almost a year, 40mg every day, and I stopped taking them three days ago. Can I take diphenhydramine or cinnarzine to help?
Hello,
This is always a problem when antidepressants are stopped cold turkey after using them for many months or years.
Ideally withdrawing from such type of drugs is a very slow method and has to be done in a disciplined way.
You should have withdrawn from drug by reducing it by 5 mg every month...
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What happens if I withraw cymbalta 30, I was taking for 6 month
Brief Answer:
Hi and welcome to XXXXXXX

Detailed Answer:
Well cymbalta is known antidepreesant that have unpleasant withdrawal symptoms. Of course, it is individual and depends from man to man. In some people there is no any difficulty but most in those that were taking it for less than 3 months....
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Hello, I d like to know what the best advice for weaning myself off of seroquel XR, I do not have insurance so please don t advise me to see a doctor, I have enough doses to last me long enough for about 2 month, I have already come down from 450mg to 250mg, I plan to drop another 50 MG this upcoming monday, my biggest problem is that I use the seroquel mainly for sleep, what is the best way to assure that I do not get terrible withdrawal symptoms when I do finally take my last dose of seroquel XR. Also I d like to know what the best recommendation would be for an over the counter sleep aid, something that I can take for the long haul and for it to be safe and non habit forming. Thank you for your time.
Hello and welcome to Healthcare Magic. Thanks for your query.

Firstly, Seroquel (Quetiapine) is an anti-psychotic medication given for certain specific psychiatric conditions called psychotic disorders. It is not a medication given for sleeping problems. Moreover, 45omg is definitely an...
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I need to know how to come off cymbalta safely. I'm down to 30 mgs for 2 days, then 60 on the 3rd day. I'm having terrible withdrawal symptoms. Dizziness, vertigo, sweating, nightmares, flashing lights in one or the other eye periodically. Headaches, severe mood swings, anger flashes. Brain zaps are the worst. My memory is coming back though and am able now to find words, phrases and frame proper sentences! I want off this drug ASAP. If I stop taking it will I have a heart attack or stroke? Would I die? If I have to go through all these symptoms after each dosage lowering I'd rather do it all at once. Thank you
Hello,
This always a problem when you try to come off these type of medications so quickly.You have to be very patient with withdrawal method otherwise rebound of withdrawl symptoms are very severe.
The best way to withdraw without attracting any symptoms is to reduce the drug by 10 mg every 15...
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