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Suggest Dosage For Tenofovir, Norvir, Lamivudine And Atazanavir

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Posted on Mon, 14 Dec 2015
Question: Hello Doctor. I'm currently on HIV PEP, and I was taking my pills everyday at 5pm (Lamevudine, Tenofovir, Atazanavir, Norvir). This morning, because of strong evidence, I thought I had missed my dose yesterday, so I took the pills at 11am. Then I found other evidence that suggested I had not missed that dose. So, basically, now I don't know if I missed my dose yesterday at 5pm (I'm almost literally 50/50% on this, siding to the possibility that I did miss it), and I took a dose today at 11am. What should I do now? Extra information: I did not had any perceivable colateral effect since the beggining of the treatment (I'm 18 days in), aside from a bit softer fezes and yellowish skin (but every other blood exam result aside from bilirubin showed perfect liver functions. The high bilirubin is because I was more susceptible given I have Gilbert's Syndrom). Just thought this might be relevant to and eventual decision that the risk of overdosing might be better than underdosing. It is already 5pm where I live, so I would appreciate a response as quickly as possible. Thank you.
doctor
Answered by Dr. Vivek Chail (7 hours later)
Brief Answer:
Take next dose at 5 pm tomorrow

Detailed Answer:
Hi,
Thanks for writing in to us.

I have read through your query in detail.
Please find my observations below.

1. It is understood that you took your medicine at 5 pm yesterday and then forgot about it. This caused doubt and to be safe you swallowed the medication at 11 am today. Then you confirmed and are sure that you took the medicine yesterday.

2. In the above situation it is better if you skip the 5 pm dose today and take the regular dose at 5 pm tomorrow.

3. Since you have taken medicine at 11 am therefore there will be some medicine in your system. Slight under dosing is always better than taking double dose on a single occasion. Please make sure you write down in a paper after taking medicine to avoid doubt.

Hope your query is answered.
Please do write back if you have any doubts.

Regards,
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Vivek Chail (14 hours later)
Hello Dr. XXXXXXX

thanks for replying. Actually, in the end, I was not sure wheter I had taken the dose the day before yesterday or not (I was 50/50% on this, but more inclined to think that I did forget to take it). Aditionally, because I wasn't getting the aswer (I know it was kind of a last minute request), I ended up taking my dose yesterday at 8pm.

So, just so you can get the full picture clearly:

Saturday 21, 5pm - Not sure if I did take my pills or not (50/50%)
Sunday 22, 11am - Because I wasn't sure, I took a dose
Sunday 22, 8pm - I wasn't sure what to do, so I took another dose (I did read it online that if I had forget to take a dose, I should take it as soon as possible and continue all other regular doses)

It's Monday 23, 3pm where I live now. What should I do next? Resume my 5pm doses, or continue taking them at 8pm?
doctor
Answered by Dr. Vivek Chail (8 minutes later)
Brief Answer:
Please continue next dose at 5 pm like before

Detailed Answer:
Hi,
Thanks for writing back with an update.

1. If you have taken the medicine on Sunday 8 pm then it makes sense to take next dose Monday 5 pm so that the regularity and timing is maintained.

2. You have taken 3 doses in 2 days but this will not affect your health significantly.

3. Taking it at 5 pm Monday will also not affect your health. You can continue taking medicine every day at 5 pm as before.

Hope your query is answered.
Please do write back if you have any doubts.

Regards,
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Vivek Chail

Radiologist

Practicing since :2002

Answered : 6874 Questions

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Suggest Dosage For Tenofovir, Norvir, Lamivudine And Atazanavir

Brief Answer: Take next dose at 5 pm tomorrow Detailed Answer: Hi, Thanks for writing in to us. I have read through your query in detail. Please find my observations below. 1. It is understood that you took your medicine at 5 pm yesterday and then forgot about it. This caused doubt and to be safe you swallowed the medication at 11 am today. Then you confirmed and are sure that you took the medicine yesterday. 2. In the above situation it is better if you skip the 5 pm dose today and take the regular dose at 5 pm tomorrow. 3. Since you have taken medicine at 11 am therefore there will be some medicine in your system. Slight under dosing is always better than taking double dose on a single occasion. Please make sure you write down in a paper after taking medicine to avoid doubt. Hope your query is answered. Please do write back if you have any doubts. Regards,