HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Is The Presence Of Smudge Cells In A Blood Smear Test A Concern?

default
Posted on Mon, 15 May 2017
Question: Daughter is 18, bloodwork shows presence of smudge cells and rouleaux. Some sources online say smudge cells indicative of CLL most common in persons over 60.Nothing else reported abnormal, including red and white counts. Bloodwork was occasioned by chronic sore throat and inflamed tonsils. Other complaints include fatigue, IBS, and "sweats." No family history of CLL or other blood and marrow cancers.

How likely is the presence of smudge cells and rouleaux to indicate CLL?
doctor
Answered by Dr. Deepak Sundriyal (2 hours later)
Brief Answer:
Hello dear. Get a repeat blood test done

Detailed Answer:
Hello dear. I have gone through the details. As rightly said, smudge cells(degenrating cells) are seen in chronic lymphocytic leukemia and rouleax formation can be seen in infections. So only point of concern is smudge cells. However, chronic lymphocytic leukemia never occurs in age below 60 years and hence reports seems to be false or some mixed up from another patient. Moreover smudge cells can be seen in normal blood also but in very low numbers, and also in infections. A repeat blood test can be done to allay the anxiety.
Thanks and regards
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Deepak Sundriyal

Oncologist

Practicing since :2005

Answered : 1617 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Is The Presence Of Smudge Cells In A Blood Smear Test A Concern?

Brief Answer: Hello dear. Get a repeat blood test done Detailed Answer: Hello dear. I have gone through the details. As rightly said, smudge cells(degenrating cells) are seen in chronic lymphocytic leukemia and rouleax formation can be seen in infections. So only point of concern is smudge cells. However, chronic lymphocytic leukemia never occurs in age below 60 years and hence reports seems to be false or some mixed up from another patient. Moreover smudge cells can be seen in normal blood also but in very low numbers, and also in infections. A repeat blood test can be done to allay the anxiety. Thanks and regards