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Does Prostitis Elevate PSA Level?

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Posted on Sat, 27 Sep 2014
Question: I was diagnosed with uti infection (klebsiella pneumoniae) now they think I have prostitis..I was on antibiotics for 6 weeks...4 weeks after the infection..I started having discomfort around the anus when sitting.
My doctor referred me to urologist. ..he did a cystoscopy ..bladder and Prostate looked normal, when he performed DRE He felt that the right side was abnormal..he ordered me to to get PSA test done..he told the level might be high because of the infection, infection or antibiotics.
My PSA was 5..he said it's not that high and performed another DRE test ...he said he does not think it's something bad..my abnormality could be due an abscess..he said he does not feel that my prostate has any signs of cancer abnormality. Now I'm having an ultrasound done after tomorrow.
blood test in 5 weeks..and i will see the urologist on the 22nd of October
My question is can prostitis cause this ?? Does prostitis elevate the PSA level?? Do you think I should Take a longer course of antibiotics? ? What do you about prostate abscess? ?
doctor
Answered by Dr. Dr. P. T. Patil (2 hours later)
Brief Answer:
Prostatitis does elevate PSA.

Detailed Answer:
Hello
Thanks for your query,based on the facts that you have posted it appears that you have been treated with antibiotics for Prostatitis.You have already finished a course of Ciprofloxacin for 4 weeks and you recent serum PSA is reported to be 5

I shall be happy if you can post me few more details to help me in making comments on your problem.
1) Was Serum PSA done before starting Ciprofloxacin ? if yes what was the report?
2) Was Trans Rectal Ultrasound Scanning (TRUS) done at any time before diagnosis of Prostatitis?
3)Was swab test and culture of the urethral discharge collected after DRE done to confirm the diagnosis of Prostatitis?

Since you are feeling better after taking antibiotics for 4 weeks it suggests that infection is getting cleared off .As such prostatitis takes long time to get cured completely and sometimes patient has to take antibiotics and anti inflammatory medications for 3-4 months .

I would like to answer your queries point to point.
1) Can prostatitis cause this ?
Ans_ Yes prostatitis cause these symptoms like perineal pain ,pain in penis ,pain around anus etc
2) Does Prostatitis elevate PSA level?
Ans -Yes Prostatitis does raise PSA level .
3) Shall I take antibiotics for longer duration?
Ans -Yes sometimes one has to take antibiotics for 3-4 months for complete cure.
4) About Prostate abscess?
Ans -Prostatic abscess can be diagnosed on DRE and is confirmed only on Trans Rectal Ultrasound scanning .

Please repeat your Serum PSA at regular intervals of every month.In case If there is persistent raising trend in PSA levels one has to think of doing Ultrasound guided multi core Prostate biopsy to rule out Cancer of prostate.

I would rather suggest you to do culture and sensitivity of urethral discharge to find out the organisms causing this infection and antibiotics to which they are sensitive to so that you can take appropriate antibiotics as per culture report.to combat infection earlier.

Hope I have answered your query ,please feel free to ask if you have more questions ,
I shall be happy to help you
Thanks and Regards.
Dr.Patil.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. P. T. Patil (16 hours later)
Hi and thank you for the update.i will provide you with
More and accurate information:
1-I'm still on antibiotics, today is going to be my
Last day (it would be six weeks )
2- my PSA was done while I was still on antibiotics, and 15 mins after having a cystoscopy done (he told me
That my PSA might be elevated because if the cystoscopy)
To be honest I don't know why he made me do the PSA knowing that it might be high because of the infection and because of the cystoscopy. He should have waited at least 3 day so my PSA can go down to normal level.

3-i did not have any TRUS done to confirm the diagnosis of prostitis. .i was diagnosed with Uti infection and then i saw different doctors in ER..
everytime i had different opinions based on DRE
Exam.
the TRUS I'm having it tomorrow for the first time.
now i have discomfort ans sometimes a bit of mild pain in my anus area..the discomfort started a month ago and that's the reason why i think I'm not healing completely.
The urologist wrote on TRUS request this" unsual
case pelvic pain..very abnormal feel right lobe of prostate..prostate abscess? ?"
This the info that I wanted to give you in order to more
Clarification.
I don't know why he wrote pelvic pain because I only feel discomfort...and i don't why an ultrasound was not at very beginning.
Now if the TRUS confirm an abscess? ? Should I wait or should I go to ER..I live in Canada and my next appointment with my urologist is until next October 22nd
Thank you
doctor
Answered by Dr. Dr. P. T. Patil (13 minutes later)
Brief Answer:
Please go ahead and getTRUS done .

Detailed Answer:
Hello
Thanks for new information .
Your serum PSA is likely to be high due to infection (Prostatitis) and cystoscopy.

Please go ahead and get TRUS done and do write me about the findings .I shall be happy to guide you regarding further treatment after going through report.

If prostatic abscess is confirmed you will need to drain it endoscopicaly.
Thanks and Regards,
Dr.Patil.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. P. T. Patil (28 hours later)
Hi,
I had TRUS done today..and was told that there is no
Abscess in the prostate ( I didn't get a copy of the report
It takes 4 days he said)
now that I ended my course of antibiotics and l still feel
Discomfort when sitting ..what should I do??
doctor
Answered by Dr. Dr. P. T. Patil (4 hours later)
Brief Answer:
Continue antibiotics foe 2 mwore weeks.

Detailed Answer:
Hello
Thanks for writing again .Continue taking antibiotics for 2 more weeks .If discomfort persists I would advise you to get prostatic massage done every day.This is the practice I am following for my patients with chronic Prostatitis since last 40 years and gives encouraging results.
prostate massage reduces prostate congestion and there by helps to relieve pelvic pain and discomfort..You can try this .
Thanks and Regards.
Dr.Patil.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. P. T. Patil (40 minutes later)
Hello again,
So it means I have to back to ER in order to get more
Antibiotics.
I will try tomorrow. .so with two more weeks it would
Have been 8 weeks of antibiotics in total.
doctor
Answered by Dr. Dr. P. T. Patil (20 minutes later)
Brief Answer:
Please go ahead and get antibiotics.

Detailed Answer:
Hello
Thanks for writing again.Take antibiotics for 2 more weeks .
Thanks and Regards.
Dr.Patil.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. P. T. Patil (39 hours later)
Hi Doctor XXXXXXX
How high a PSA would go up after a DRE and Cystoscopy were done simultaneously on me??
Would that add to my previous PSA levels knowing that I have a complication of uti

Hi
I'm taking septra sd is it a good antibiotic for uti and prostatitis?
Thank you.
doctor
Answered by Dr. Dr. P. T. Patil (14 hours later)
Brief Answer:
PSA increases after DRE and cystoscopy.

Detailed Answer:
Hello
Thanks for follow up. PSA increases after handling of Prostate either by DRE or cystoscopy.

You can take Septran Ds for 2-3 weeks.
Thanks and regards.
Dr.Patil.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. P. T. Patil (2 days later)
Hi Doctor,
i saw my family doctor yesterday and he wants me to do PSA test knowing that i just had TRUS done 3 days ago... i told him that because of TRUS i should wait longer beofre having PSA test but he said its ok to do it.
whats your opinion ?

Thank you
doctor
Answered by Dr. Dr. P. T. Patil (1 hour later)
Brief Answer:
You can get it done now,Hello

Detailed Answer:
Hello
Thanks for follow up.Since three days are over after doing TRUS you can get it done after 2 more days.
Please post report of TRUS.
Thanks and Regards.
Dr.Patil.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Dr. P. T. Patil (36 minutes later)
what if my prostatitis is not cured yet ?? will affect my PSA levels?
i will get TRUS report today and i will post it today and will wait for you opinion
thank you!!
the ultrasound report reads as follow:
the bladder walls are normal but the bladder is poorly distended with a volume only of 85 cc, post void residual is 10 cc indicating a retention up 5 %.

the prostate is mildly enlarged with a volume of 30 cc, it is grossly homogeneous with no nodularities but it has some calcification
There are no pelvic masses
SUMMARY
Mild prostatic hypertrophy with a small retention in the bladder after voiding.


let me know your opinion and proper treatment

doctor
Answered by Dr. Dr. P. T. Patil (7 hours later)
Brief Answer:
Continue taking antibiotic for 2 more weeks.

Detailed Answer:
Hello
Thanks for follow up.
Your ultrasound report suggests mild enlargement of prostate with post void residual urine of 10 ml a ,calcification in prostate is suggestive of Chronic infection of prostate.

Continue taking antibiotics for 2 more weeks along with Tomsulosin once a day
Thanks and Regards.
Dr.Patil.
Note: Consult a Urologist online for consultation about prostate and bladder problems, sexual dysfunction, kidney stones, prostate enlargement, urinary incontinence, impotence and erectile dysfunction - Click here.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Dr. Dr. P. T. Patil

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Does Prostitis Elevate PSA Level?

Brief Answer: Prostatitis does elevate PSA. Detailed Answer: Hello Thanks for your query,based on the facts that you have posted it appears that you have been treated with antibiotics for Prostatitis.You have already finished a course of Ciprofloxacin for 4 weeks and you recent serum PSA is reported to be 5 I shall be happy if you can post me few more details to help me in making comments on your problem. 1) Was Serum PSA done before starting Ciprofloxacin ? if yes what was the report? 2) Was Trans Rectal Ultrasound Scanning (TRUS) done at any time before diagnosis of Prostatitis? 3)Was swab test and culture of the urethral discharge collected after DRE done to confirm the diagnosis of Prostatitis? Since you are feeling better after taking antibiotics for 4 weeks it suggests that infection is getting cleared off .As such prostatitis takes long time to get cured completely and sometimes patient has to take antibiotics and anti inflammatory medications for 3-4 months . I would like to answer your queries point to point. 1) Can prostatitis cause this ? Ans_ Yes prostatitis cause these symptoms like perineal pain ,pain in penis ,pain around anus etc 2) Does Prostatitis elevate PSA level? Ans -Yes Prostatitis does raise PSA level . 3) Shall I take antibiotics for longer duration? Ans -Yes sometimes one has to take antibiotics for 3-4 months for complete cure. 4) About Prostate abscess? Ans -Prostatic abscess can be diagnosed on DRE and is confirmed only on Trans Rectal Ultrasound scanning . Please repeat your Serum PSA at regular intervals of every month.In case If there is persistent raising trend in PSA levels one has to think of doing Ultrasound guided multi core Prostate biopsy to rule out Cancer of prostate. I would rather suggest you to do culture and sensitivity of urethral discharge to find out the organisms causing this infection and antibiotics to which they are sensitive to so that you can take appropriate antibiotics as per culture report.to combat infection earlier. Hope I have answered your query ,please feel free to ask if you have more questions , I shall be happy to help you Thanks and Regards. Dr.Patil.