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Do Prozac, Topamax And Hydroxyzine Cause Any Liver Or Kidney Damage?

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Posted on Fri, 10 Jun 2016
Question: will any of these medications cause any liver or kidney damage ?
Prozac-pulvule- 20mg
Topamax-25mg-tab
hydroxyzine pam 25mg
nabumetone-750mg-tabmethocarbam-500mg-tab
allopurinol-300mg-tab
Zyprexa-15mg
buspirone-hcl-10mgtab
doctor
Answered by Dr. Panagiotis Zografakis (25 minutes later)
Brief Answer:
some of them may do so

Detailed Answer:
Hello,

prozac may rarely cause renal damage (albuminuria, oliguria) and liver problems (abnormal liver function tests, serious liver injury, cholestatic jaundice).
Topamax may cause renal stones (rarely too) and liver injury (less than 0.1% of patients).
Hydroxyzine does not have serious renal or liver side effects but it may affect those organs indirectly. For example urinary retention may affect the kidneys if left untreated for long.
Nabumetone may cause acute renal failure (particularly in dehydrated patients) and liver injury with increased liver function tests.
Allopurinol has relatively frequent serious side effects. Serious renal damage may occur in 1-10% of patients using it. Liver injury may occur in up to 10% of patients. Very serious liver injury occurs in approximately 0.1%.
Zyprexa may cause liver enzyme disorders relatively frequently. Renal damage is not expected with normal use (only indirect damage like with hydroxyzine).
Buspirone is probably the safest drug regarding liver and renal side effects from the aforementioned ones. No serious liver or renal side effect is expected.

I hope you find my answer helpful!
You can contact me again, if you'd like any clarification or further information.

Kind Regards!
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3809 Questions

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Do Prozac, Topamax And Hydroxyzine Cause Any Liver Or Kidney Damage?

Brief Answer: some of them may do so Detailed Answer: Hello, prozac may rarely cause renal damage (albuminuria, oliguria) and liver problems (abnormal liver function tests, serious liver injury, cholestatic jaundice). Topamax may cause renal stones (rarely too) and liver injury (less than 0.1% of patients). Hydroxyzine does not have serious renal or liver side effects but it may affect those organs indirectly. For example urinary retention may affect the kidneys if left untreated for long. Nabumetone may cause acute renal failure (particularly in dehydrated patients) and liver injury with increased liver function tests. Allopurinol has relatively frequent serious side effects. Serious renal damage may occur in 1-10% of patients using it. Liver injury may occur in up to 10% of patients. Very serious liver injury occurs in approximately 0.1%. Zyprexa may cause liver enzyme disorders relatively frequently. Renal damage is not expected with normal use (only indirect damage like with hydroxyzine). Buspirone is probably the safest drug regarding liver and renal side effects from the aforementioned ones. No serious liver or renal side effect is expected. I hope you find my answer helpful! You can contact me again, if you'd like any clarification or further information. Kind Regards!