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Do Lipitor, Famotidine, Flomax And Zoloft Cause Liver Damage?

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Posted on Tue, 29 Dec 2015
Question: Can any of my meds cause liver damage?

famotidine
losartan
sertraline
Azopt (brinzolamide ophthalmic)
Flomax (tamsulosin)
Lipitor (atorvastatin)
Lumigan (bimatoprost ophthalmic)
Ofev (nintedanib)
Remeron (mirtazapine)
Requip (ropinirole)
Serax (oxazepam)
Zoloft (sertraline)
doctor
Answered by Dr. Bonnie Berger-Durnbaugh (1 hour later)
Brief Answer:
Lipitor may be biggest concern, a few other meds can cause liver problems

Detailed Answer:
Hello XXXXXXX

Several of your medications are metabolized (broken down, processed) by the liver, and so they have the potential for causing liver stress or problems.

The one that stands out in your list is Lipitor as that one definitely can cause liver damage. All of the statin medications can.

The ophthalmic meds I would not be concerned about.

The oral meds you take that are processed by the liver to varying degrees are:
Famotidine
Losartan
Sertraline
Flomax
Ofev
Remeron
Requip
Oxazepam
Zoloft

If you have liver problems, if there is any way to get off of the statin (Lipitor) that might take care of the problem.

You can also ask the pharmacist where you get your medications filled to look at your list of meds (they would have this in their computer) when he or she has time, and give you an idea of how likely some of the other meds, that are processed by the liver, are to cause liver damage. A pharmacist knows the finer details of which meds can cause problems.

If you want the opinion of a gastroenterologist on this HealthcareMagic site, you can close the discussion with me, repost what you wrote as a new question, and write in the first line "For Gastoenterologist or Hematologist ONLY". They will respond, but it might take some time, as they aren't on the site looking at questions all the time.

I hope this information helps.





Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Bonnie Berger-Durnbaugh (44 hours later)
Hello Dr. XXXXXXX

Thank you for your prompt reply. My meds are mostly low-dose. For example, I take Zoloft 50mg q.d. And Lipitor 10mg q.d. Does this fact make a difference re liver stress? Per your suggestion, I will refer my question to a Kaiser Pharmicist.

BTW my son, Gedge, has a dual appointment as a reconstructive/peripheral nerve surgeon and oncologist at XXXXXXX where he is Director of Breast Reconstruction, among other things. Almost exclusively free-flaps. He's figured out how to preserve neural-sensation to the breast area using real-time CT scanning. He has not figured out how to maintain the erogenous sensation, but he's working on it. Success is elusive. He is very interested in women's health issues.
doctor
Answered by Dr. Bonnie Berger-Durnbaugh (3 hours later)
Brief Answer:
Yes, the dosage does make a difference.

Detailed Answer:
Yes, the dosage of medications usually does have an effect on how hard it is on the liver or kidneys which are the 2 main organs that break down or process medications.

You must be very proud of your son! The work that he is doing is important for the well being of many women.

Best regards,
Bonnie Berger-Durnbaugh, MD
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Bonnie Berger-Durnbaugh

General & Family Physician

Practicing since :1991

Answered : 3134 Questions

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Do Lipitor, Famotidine, Flomax And Zoloft Cause Liver Damage?

Brief Answer: Lipitor may be biggest concern, a few other meds can cause liver problems Detailed Answer: Hello XXXXXXX Several of your medications are metabolized (broken down, processed) by the liver, and so they have the potential for causing liver stress or problems. The one that stands out in your list is Lipitor as that one definitely can cause liver damage. All of the statin medications can. The ophthalmic meds I would not be concerned about. The oral meds you take that are processed by the liver to varying degrees are: Famotidine Losartan Sertraline Flomax Ofev Remeron Requip Oxazepam Zoloft If you have liver problems, if there is any way to get off of the statin (Lipitor) that might take care of the problem. You can also ask the pharmacist where you get your medications filled to look at your list of meds (they would have this in their computer) when he or she has time, and give you an idea of how likely some of the other meds, that are processed by the liver, are to cause liver damage. A pharmacist knows the finer details of which meds can cause problems. If you want the opinion of a gastroenterologist on this HealthcareMagic site, you can close the discussion with me, repost what you wrote as a new question, and write in the first line "For Gastoenterologist or Hematologist ONLY". They will respond, but it might take some time, as they aren't on the site looking at questions all the time. I hope this information helps.