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Diagnosed With Chronic Lymphocytic Leukemia. Awaiting Bone Marrow Biopsy Results. Is Chronic Dry Cough A Symptom?

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Posted on Wed, 27 Jun 2012
Question: I was just diagnosed with chronic lymphocytic leukemia (CLL). I've already been to MD XXXXXXX in Houston and are awaiting the results. I've had a chronic, dry cough for 2 months. Is it related to the CLL and what can be done about it?
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Answered by Dr. Gyanshankar Mishra (4 hours later)
Hi,

Thanks for posting your query.

After going through your query, I would like to make the following comments:

Given your history, there are several possibilities that need to be considered:
a. Cough induced due to treatment of lisinopril: Lisinopril is an angiotensin converting enzyme inhibitor (ACE inhibitor) and dry cough is a very commonly complication seen in people who take lisinopril. The only definitive treatment of this is stopping therapy and switching you to an alternative drug. I would suggest that you visit your physician who will be able to guide you better.
b. A secondary respiratory infection.
c. There is a rare possibility of lung involvement by the chronic lymphocytic leukaemia.

I would suggest the following
a. Consult your physician about replacing lisinopril.
b. Get a chest Xray and your blood counts done. In the blood counts report, we need to look specifically for the eosinophil count.
d. A high resolution computerised tomography scan (HRCT) of thorax will pick up any lung involvement by your CLL.
I hope I have answered your query. I will be glad to answer any follow up queries.

Please accept my answer if you have no follow up queries.

Regards

Dr. Gyanshankar Mishra
MBBS MD DNB

Above answer was peer-reviewed by : Dr. Aparna Kohli
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Answered by
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Dr. Gyanshankar Mishra

Pulmonologist

Practicing since :2003

Answered : 600 Questions

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Diagnosed With Chronic Lymphocytic Leukemia. Awaiting Bone Marrow Biopsy Results. Is Chronic Dry Cough A Symptom?

Hi,

Thanks for posting your query.

After going through your query, I would like to make the following comments:

Given your history, there are several possibilities that need to be considered:
a. Cough induced due to treatment of lisinopril: Lisinopril is an angiotensin converting enzyme inhibitor (ACE inhibitor) and dry cough is a very commonly complication seen in people who take lisinopril. The only definitive treatment of this is stopping therapy and switching you to an alternative drug. I would suggest that you visit your physician who will be able to guide you better.
b. A secondary respiratory infection.
c. There is a rare possibility of lung involvement by the chronic lymphocytic leukaemia.

I would suggest the following
a. Consult your physician about replacing lisinopril.
b. Get a chest Xray and your blood counts done. In the blood counts report, we need to look specifically for the eosinophil count.
d. A high resolution computerised tomography scan (HRCT) of thorax will pick up any lung involvement by your CLL.
I hope I have answered your query. I will be glad to answer any follow up queries.

Please accept my answer if you have no follow up queries.

Regards

Dr. Gyanshankar Mishra
MBBS MD DNB