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Can Dextromethorphan, Acetaminophen And Lexapro Be Taken Together?

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Posted on Thu, 2 Feb 2017
Question: I have a cold and wish to take a cold relief formula hat contains dextromethorphan and guaifenesin and phenylephrine as well as acetaminophen in it. I am on Lexapro. 10 mg a day. Is it ok to take the cold meds?
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Answered by Dr. Michelle Gibson James (27 minutes later)
Brief Answer:
dextromethorphan and lexapro interact

Detailed Answer:
HI, thanks for using healthcare magic

There is a risk of a possible serious interaction between dextromethorphan and lexapro (escitalopram).

Both of these medications can increase the level of a chemical called serotonin and potentially cause the serotonin syndrome
Serotonin syndrome can cause tremors, increase body temperature, confusion, increased heart rate and blood pressure, confusion, nausea, hallucination, diarrhea.

You should consider using a cough mixture without the dextromethorphan.

I hope this helps, feel free to ask any other questions
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Michelle Gibson James

General & Family Physician

Practicing since :2001

Answered : 16808 Questions

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Can Dextromethorphan, Acetaminophen And Lexapro Be Taken Together?

Brief Answer: dextromethorphan and lexapro interact Detailed Answer: HI, thanks for using healthcare magic There is a risk of a possible serious interaction between dextromethorphan and lexapro (escitalopram). Both of these medications can increase the level of a chemical called serotonin and potentially cause the serotonin syndrome Serotonin syndrome can cause tremors, increase body temperature, confusion, increased heart rate and blood pressure, confusion, nausea, hallucination, diarrhea. You should consider using a cough mixture without the dextromethorphan. I hope this helps, feel free to ask any other questions