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Are There Direct Interactions Between Diflucan, Spironolactone And Levofloxacin?

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Posted on Mon, 26 Dec 2016
Question: Is it a bad idea to take spironolactane, levofloxscin and diflucan at same time?
I have hydrops and sinus plus severe tinnitus. Do these drugs amp up tinnitus?
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Answered by Dr. Saddiq Ulabidin (5 hours later)
Brief Answer:
Can be used for shorter interval together

Detailed Answer:
Hi! Welcome to health care magic! Thanks for sharing your concerns with us. We will try to help you in best way possible. First of all, it is sad to know what you had been experiencing lately.

Safety profile and dug interactions is complex subject as most of the drugs have their unpleasant effects on almost every system of the body but most of them are extremly rarer occurrences so most of the times its clinicians domain to overweight the benefits over the possible risks and may be prescribed hence. Only exceptions are common side effects or life threatening complications which are avoided hence. The drug combination you mentioned can potentiate symptoms of tinnitus specially levofloxacin but it's use for short interval can be continued keeping in view the reason for its advisement and if other alternate antibiotic can't be used (as in cases of cultures and sensitivity showing sensitivity only to it or no oral alternate is avaialbe) or if first few doses are tolerated well but if symptoms are debilitating or worsening, same can be avoided.

Hope this has answered your query, if you have any more questions, feel free to ask. Regards.
Note: Consult an experienced Otolaryngologist / ENT Specialist online for further follow up on ear, nose, and throat issues - Book a Call now.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
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Dr. Saddiq Ulabidin

General & Family Physician

Practicing since :2011

Answered : 3941 Questions

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Are There Direct Interactions Between Diflucan, Spironolactone And Levofloxacin?

Brief Answer: Can be used for shorter interval together Detailed Answer: Hi! Welcome to health care magic! Thanks for sharing your concerns with us. We will try to help you in best way possible. First of all, it is sad to know what you had been experiencing lately. Safety profile and dug interactions is complex subject as most of the drugs have their unpleasant effects on almost every system of the body but most of them are extremly rarer occurrences so most of the times its clinicians domain to overweight the benefits over the possible risks and may be prescribed hence. Only exceptions are common side effects or life threatening complications which are avoided hence. The drug combination you mentioned can potentiate symptoms of tinnitus specially levofloxacin but it's use for short interval can be continued keeping in view the reason for its advisement and if other alternate antibiotic can't be used (as in cases of cultures and sensitivity showing sensitivity only to it or no oral alternate is avaialbe) or if first few doses are tolerated well but if symptoms are debilitating or worsening, same can be avoided. Hope this has answered your query, if you have any more questions, feel free to ask. Regards.