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Are Androgen Receptors Always Present In Androgen Target Tissues By Birth?

Posted on Fri, 13 Feb 2015

Question: Are androgen receptors always present in androgen target tissues, even before time of high androgen circulation (puberty) ?

Answered by Dr. Rakesh Madhyastha (29 minutes later)

Brief Answer:
Androgen receptors

Detailed Answer:
Hello

Thanks for the query

Androgen receptors are developed at birth itself, it is always present in our body. It does not develop after androgen starts secreting in the body. It only gets activated once the androgen is released.

I hope I was of help, if you have any further queries please get back to me

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Rakesh Madhyastha (3 days later)

Thanks.

Early in male life after the 'mini puberty' ends, are androgens still secreted from gonads?

Answered by Dr. Rakesh Madhyastha (11 hours later)

Brief Answer:
Yes

Detailed Answer:
Hello

Thanks for getting back

I am sorry I did not get your question. When you say early in life, do you mean pre natal, just after birth or few months after birth?

Please get back to me, I am awaiting your reply

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Rakesh Madhyastha (7 hours later)

Hello,

I was referring to period 2year to 10 years - the juvenile phase. Do the gonads still secrete androgens during this so called ' quiescient' period?

Thanks

Answered by Dr. Rakesh Madhyastha (9 hours later)

Brief Answer:
Yes

Detailed Answer:
Hello

THanks for the query.

Gonads do secrete in small amounts during the juvenile phase.

Regards

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Rakesh Madhyastha (29 hours later)

Thanks ,

I have an intriguing query and would like your opinion on it, why does testosterone in a male baby not lead to voice change, but in teenage years it does?

Thanks and bes regards

Answered by Dr. Rakesh Madhyastha (1 hour later)

Brief Answer:
testosterone increases and so does the sensitivity

Detailed Answer:
Hello

Thanks for getting back

Because the levels of testosterone increases and so does the sensitivity of it on its acting receptors

Regards

Note: For detailed guidance on genetic screening consult a genetics specialist

Above answer was peer-reviewed by : Dr. Raju A.T