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Suggest Dosage For Rifampicin And Clindamycin

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Posted on Thu, 18 Feb 2016
Question: 2 years child presented with 39 temp and can't speak e to sore throat, tonsil : slight hypertrophied arround ++ submandibular lympadenitis,tender on exam neck , no cough,no rhinitis , chest free
admite him in pediatric woard ( had history of taking augmentine susp 3 days with no result)
wbc was 25000
gave him : paracetamol 16ml/6hours iv
clidamycin 200 mg iv/12 hour
pediatric doctor add rifampicin susp 7.5 ml /12 hours ??? is there any role for rifampicin here ??/
thanks more XXXXXXX GP
doctor
Answered by Dr. Panagiotis Zografakis (27 minutes later)
Brief Answer:
strange choice!

Detailed Answer:
Hello,

I can't comment on the dosages but the choice of rifampicin when the patient is already taking clindamycin sounds a little strange. I don't know whether they have culture results on their hands or if it's a local guideline but it's indeed strange! I can't understand why it was prescribed! What did the treating doctor say?
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (10 minutes later)
yes i agree with you i will disscus this with pediatric doctor about his advise??
and inform you
thank you very much
doctor
Answered by Dr. Panagiotis Zografakis (2 minutes later)
Brief Answer:
yes, please do

Detailed Answer:
You're welcome!

If/when you have more information, please do share it with me. I'm really curious about that.

Kind Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (17 minutes later)
hello
ofcourse i will inform you about this
our meeting will be on sunday and i will disscuss this advise with pediatric doctor
and then inform you
thanks i am a doctor and this advise was strangous for me and i try to search in internet i found rifampicin susp can given for child how had hemophilius influenza infection or tonsillitis caused by infection with nessieria
thanks more i will contact you againe sunday
by
doctor
Answered by Dr. Panagiotis Zografakis (2 minutes later)
Brief Answer:
thanks!

Detailed Answer:
I knew about Neisseria but there are far more choices with a much broader spectrum, which would sound more reasonable for a patient with a seemingly more severe disease caused by an unknown organism. So unless the colleague had either culture results (and antibiogram of course) or the obligation to follow some local guidelines there is no reasonable explanation, according to my opinion.

Best Regards!
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Panagiotis Zografakis (47 hours later)
Dear Dr Panagiotis
i discussed this adives( which was add rifampicin susp to other antibiotic for AFT
which not improved with empirical antibiotic )
clindamycin +rifampicin ) he say the causative bacteria may be not strep
rifampicin will eradicte other -ve bacteria with clidamycine
this was his idea , ofcourse i just gave the patient clidamycin 3 days wbc was 25000 on third day it was 1500 on 4th day it was 7000 , then discarge the child with follow up and contineue on augmintin susp with analgesic
this was what i promise you to share you about this case thanks more for your respons and hope we will contineue in feuture to disscuse any cases
thanks
Dr XXXXXXX
doctor
Answered by Dr. Panagiotis Zografakis (1 hour later)
Brief Answer:
still strange...

Detailed Answer:
Dr XXXXXXX

thank you very much for sharing this information with me. I still don't agree with his choice but at least there was some reasoning behind it!

Kind Regards!
Note: For further queries related to your child health, Talk to a Pediatrician. Click here to Book a Consultation.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3809 Questions

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Suggest Dosage For Rifampicin And Clindamycin

Brief Answer: strange choice! Detailed Answer: Hello, I can't comment on the dosages but the choice of rifampicin when the patient is already taking clindamycin sounds a little strange. I don't know whether they have culture results on their hands or if it's a local guideline but it's indeed strange! I can't understand why it was prescribed! What did the treating doctor say?