I had a positive Ra factor about a two years ago. My general doctor put me on plaquinel which helped with the joint pain that I have in my shoulders,elbows, wrists, hips, knees, ankles and fingers. Saw a rheumatologist nine months later and same test was negative. Now I have granuloma annular. Lately I have been breaking out in hives all over my body. It happens randomly throughout the day. Could all of this be related and should I be tested for RA again or other autoimmune diseases? I know something is wrong in my body somewhere.