Hi Welcome to HCM. I appreciate your concern for your son. Also known as Childhood neuropsychiatric syndrome, to diagnose this rare condition (1:2000) there should be 5 criteria: 1. Onset of symptoms from age 3 years to puberty 2. Presence of obsessive-compulsive disorder, Attention Deficit Hyperactive Disorder symptoms, or oppositional behaviors 3. Abrupt onset and or symptoms vary in intensity 4. Neurological abnormalities, including motor hyperactivity, or abnormal movements, such as involuntary jerky movements), other combinations of neuro-psychiatric symptoms, such as anxiety, emotional lability, bed wetting, or temper tantrums, personality changes and deterioration in math skills and handwriting 5. History of A beta-hemolytic streptococcal infection (the bacteria that causes strep throat) either by culture or other evidence of infection, such as scarlet fever or by laboratory test evidence (High ASO & DNase titres). Hope this answers your query. Best regards.