Brief answer Strict Dietary restriction with regular physical exercise Detailed answer Looking at you history of weight gain and gastrointestinal problem ( indeterminate crohn s ) i would advise you few dietary modification 1. avoid fatty and junk food like pizza, burger and fried items 2. have plenty of fluids in form of juices, soups and lukewarm water very frequently ( 5-6 liters a day) 3. do some exercises as much your body allows. 4. frequent and small meals or snacks 5. try to avoid sweets and sugar 6. take more fruits and fibers in your diet get your thyroid profile tested. hope this helps , feel free to ask for more details or further follow up thanks for using health care magic good luck