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What Is The Meaning Of This? A: Sections Show Benign
Question: what is the meaning of this?
A: Sections show benign esophageal squamous mucosa with active inflammation and reactive changes (mucosal capillary ectasia, hyperplasia of the
squamous epithelium, and rare ballooning). No goblet cell metaplasia is identified. No dysplasia is identified.
A: Sections show benign esophageal squamous mucosa with active inflammation and reactive changes (mucosal capillary ectasia, hyperplasia of the
squamous epithelium, and rare ballooning). No goblet cell metaplasia is identified. No dysplasia is identified.
Brief Answer:
Please go through detailed answer dear.
Detailed Answer:
Hello and thank you for choosing 'Ask A Doctor' service for your query my dear.
Metaplasia means a change of one type of cell into another. It's a protective phenomenon adopted by the body to prevent degeneration of the esophagus by acid refluxed from the stomach but if not treated properly in long runs increases the chances of Adenocarcinoma by 10%.
The esophagus is the food pipe, lined by a type of cell called squamous cells (they are not acid-resistant). This pipe is connected to a bag called the stomach. Now the stomach contains Columnar cells which are acid-resistant.
In patients with uncontrolled/Improperly treated reflux disease Squamous cells are replaced by Columnar cells(acid resistant) this process is called Metaplasia.
In long runs, if left untreated dysplasia can occur which is a precancerous stage.
So in short untreated Metaplasia results in Dysplasia (Lay man's language cancerous cells).
Goblet cells are found in the stomach and as per reports they are not seen in your esophagus which means that your case is in initial phases and can be controlled by the use of proper antacids with prokinetic drugs.
Reactive changes plus other terms used in the report in lay man's language mean that if not treated properly your body is getting ready to replace squamous cells with Columnar cells in the future which could be resulting in Adenocarcinoma in 10% cases.
Hope I was easy to understand,
Follow-ups are welcome.
Thank you
Please go through detailed answer dear.
Detailed Answer:
Hello and thank you for choosing 'Ask A Doctor' service for your query my dear.
Metaplasia means a change of one type of cell into another. It's a protective phenomenon adopted by the body to prevent degeneration of the esophagus by acid refluxed from the stomach but if not treated properly in long runs increases the chances of Adenocarcinoma by 10%.
The esophagus is the food pipe, lined by a type of cell called squamous cells (they are not acid-resistant). This pipe is connected to a bag called the stomach. Now the stomach contains Columnar cells which are acid-resistant.
In patients with uncontrolled/Improperly treated reflux disease Squamous cells are replaced by Columnar cells(acid resistant) this process is called Metaplasia.
In long runs, if left untreated dysplasia can occur which is a precancerous stage.
So in short untreated Metaplasia results in Dysplasia (Lay man's language cancerous cells).
Goblet cells are found in the stomach and as per reports they are not seen in your esophagus which means that your case is in initial phases and can be controlled by the use of proper antacids with prokinetic drugs.
Reactive changes plus other terms used in the report in lay man's language mean that if not treated properly your body is getting ready to replace squamous cells with Columnar cells in the future which could be resulting in Adenocarcinoma in 10% cases.
Hope I was easy to understand,
Follow-ups are welcome.
Thank you
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Above answer was peer-reviewed by :
Dr. Arnab Banerjee
Answered by
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