Brief Answer:
Fluconazole orally is preferable.

Detailed Answer:
Hello dear, welcome to Ask a doctor service.
I read your query and here is my advice.

Possibly you have used many types of topical antifungal creams or ointments or lozenges unsuccessfully.
A good alternative is to use fluconazole orally to eradicate candida albicans.
The dosage and the lasting of therapy depends on severity of infection and location.
You also can combine oral fluconazole with topical nystatin or clotrmazole or amphotercine B etc.

Hope I have answered the question.
Let me know if I can assist you further

---