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What Do Raised GM Antibody Titer Levels Indicate?

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Posted on Tue, 26 Dec 2023
Question: would you be able to find me a neurologist who understands motor and sensory neuropathy and test results?

Is there a neurologist who is able to interpret my test results I just uploaded?
doctor
Answered by Dr. Ishu Bishnoi (1 hour later)
Brief Answer:

Results interpretation

Detailed Answer:

Hi,

Your antibody test results are showing two positive results

- GM 1 antibody (IgM) titer raised
- Ganglioside Asialo GM1 antibody titer raised

These two antibodies are found positive in case of autoimmune inflammatory demyelinating neuropathy. One of the common disorder is "Gullain Barre syndrome".

Compared with the controls, the median titre of GM1 was significantly higher in patients with multiple sclerosis, rheumatoid arthritis, primary Sjögren's syndrome and systemic lupus erythematosus.

In your case, the idiopathic neuropathy is most probably due to any of above-mentioned syndrome. Your rest antibodies were negative and not suggesting any particular syndrome.

Your history report is suggesting
- operated breast with benign calcification,
- benign thyroid nodule,
- normal carotid doppler,
- normal blood tests,
- normal urine tests,
- raised cholesterol,
- the normal level of CA 125 and no diabetes mellitus.

Hope I have answered your query.

Take care

Regards,
Dr Ishu Bishnoi, Neurologist, Surgical
Above answer was peer-reviewed by : Dr. Prasad
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Answered by
Dr.
Dr. Ishu Bishnoi

Neurologist, Surgical

Practicing since :2007

Answered : 901 Questions

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What Do Raised GM Antibody Titer Levels Indicate?

Brief Answer: Results interpretation Detailed Answer: Hi, Your antibody test results are showing two positive results - GM 1 antibody (IgM) titer raised - Ganglioside Asialo GM1 antibody titer raised These two antibodies are found positive in case of autoimmune inflammatory demyelinating neuropathy. One of the common disorder is "Gullain Barre syndrome". Compared with the controls, the median titre of GM1 was significantly higher in patients with multiple sclerosis, rheumatoid arthritis, primary Sjögren's syndrome and systemic lupus erythematosus. In your case, the idiopathic neuropathy is most probably due to any of above-mentioned syndrome. Your rest antibodies were negative and not suggesting any particular syndrome. Your history report is suggesting - operated breast with benign calcification, - benign thyroid nodule, - normal carotid doppler, - normal blood tests, - normal urine tests, - raised cholesterol, - the normal level of CA 125 and no diabetes mellitus. Hope I have answered your query. Take care Regards, Dr Ishu Bishnoi, Neurologist, Surgical