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Should I Discontinue Taking Buspirone HCL When I Start Taking Tramadol HCL?

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Posted on Mon, 4 Apr 2022
Question: I just started taking Tramadol HCL 50 mg yesterday. I have been taking Buspirone Hcl for more than a year. Should I d/c the Buspirone?
doctor
Answered by Dr. Shinas Hussain (2 hours later)
Brief Answer:
Better to discontinue buspirone and restart after a while.

Detailed Answer:

Hello,

Buspirone and oral tramdol interact with each other and sometimes result in serious adverse effects.
Buspirone oral and tramadol oral both increases serotonin levels in the body and can results in a life threatening condition known as “serotonin syndrome”.
You can consult your physician and ask for substitutes for Tramadol or stop the Buspirone for a short period and restart when you are off tramadol.

Wishing you good health.
Thanks
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Shinas Hussain (59 minutes later)
What is ". Seratonin syndrone"?
doctor
Answered by Dr. Shinas Hussain (16 hours later)
Brief Answer:
Given

Detailed Answer:

Hello,

"Serotonin syndrome" is a group of symptoms that develops after taking certain drugs that increases the secretion of seratonin ( a neurotransmitter in the body).
The symptoms starts immediately after taking the medicines and includes elevated heart rate, dilated pupil, sweating, nausea and vomiting.
In case of similar symptoms after taking any of your drug, you can stop the particular drug and rush to your doctor.

Hope I have answered your query. Wishing you good health.
Thanks
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Nagamani Ng
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Answered by
Dr.
Dr. Shinas Hussain

General Surgeon

Practicing since :2015

Answered : 23672 Questions

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Should I Discontinue Taking Buspirone HCL When I Start Taking Tramadol HCL?

Brief Answer: Better to discontinue buspirone and restart after a while. Detailed Answer: Hello, Buspirone and oral tramdol interact with each other and sometimes result in serious adverse effects. Buspirone oral and tramadol oral both increases serotonin levels in the body and can results in a life threatening condition known as “serotonin syndrome”. You can consult your physician and ask for substitutes for Tramadol or stop the Buspirone for a short period and restart when you are off tramadol. Wishing you good health. Thanks