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Please Provide The Prognosis And Possible Complication Of Giant Cell

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Posted on Mon, 17 Feb 2020
Question: Please provide the prognosis and possible complication of Giant cell tumor of lower end of left tibia share the possibilities of recurrence in other parts
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Answered by Dr. AJEET SINGH (5 hours later)
Brief Answer:
?Prognosis,complications,recurrence of Giant cell tumor

Detailed Answer:
Hi....
Welcome to "Ask a Doctor" service.
I am Dr Ajeet XXXXXXX

I have gone through your query/report and here is my opinion.

Giant cell tumors (GCT) are formed by collection of multi nucleated abnormal cells called giant cells or histiocytes.
Giant cell tumors exclusively occur at the end of the long bones (epiphysis) directly next to the joints.
They are non cancerous but are very aggressive in nature.

Prognosis of GCT is good if treated aggressively and with a multidisciplinary approach.
Surgical modality of treatment is surgical removal,extended curettage,bone grafting and local reconstruction.
Non surgical treatments include radiotherapy (Tumors that can't be removed surgically can often be controlled and sometimes destroyed with radiation therapy),tumor embolization and injectable medications (like Zoledronate and monoclonal antibodies)against tumor cells.

Outcome of treatment depends on many factors...,,like age,status of parathyroid ,size of tumor, location of the tumor,staging of tumor and method of treatment used.
Your clinician would be in a better position to reveal the details.

There are high possibilities of GCT recurrence so patient needs regular follow up and screenings.

Complications include pathological fractures,bone infection (which is deep seated and difficult to treat),micro embolization of giant cells to lungs,lung failure and recurrence of primary tumor.

Hope that I have answered your query.
If you have any doubts,please let me know.

Stay healthy and stay blessed.
Regards.
Note: For further queries, consult a joint and bone specialist, an Orthopaedic surgeon. Book a Call now.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
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Dr. AJEET SINGH

General & Family Physician

Practicing since :1994

Answered : 2151 Questions

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Please Provide The Prognosis And Possible Complication Of Giant Cell

Brief Answer: ?Prognosis,complications,recurrence of Giant cell tumor Detailed Answer: Hi.... Welcome to "Ask a Doctor" service. I am Dr Ajeet XXXXXXX I have gone through your query/report and here is my opinion. Giant cell tumors (GCT) are formed by collection of multi nucleated abnormal cells called giant cells or histiocytes. Giant cell tumors exclusively occur at the end of the long bones (epiphysis) directly next to the joints. They are non cancerous but are very aggressive in nature. Prognosis of GCT is good if treated aggressively and with a multidisciplinary approach. Surgical modality of treatment is surgical removal,extended curettage,bone grafting and local reconstruction. Non surgical treatments include radiotherapy (Tumors that can't be removed surgically can often be controlled and sometimes destroyed with radiation therapy),tumor embolization and injectable medications (like Zoledronate and monoclonal antibodies)against tumor cells. Outcome of treatment depends on many factors...,,like age,status of parathyroid ,size of tumor, location of the tumor,staging of tumor and method of treatment used. Your clinician would be in a better position to reveal the details. There are high possibilities of GCT recurrence so patient needs regular follow up and screenings. Complications include pathological fractures,bone infection (which is deep seated and difficult to treat),micro embolization of giant cells to lungs,lung failure and recurrence of primary tumor. Hope that I have answered your query. If you have any doubts,please let me know. Stay healthy and stay blessed. Regards.