question-icon

JUST GOT PATHOLOGY RESULTS, BREAST BIOPSY; CD20: REACTIVE IN B

default
Posted on Wed, 27 Mar 2019
Question: JUST GOT PATHOLOGY RESULTS, BREAST BIOPSY; CD20: REACTIVE IN B CELLS, CD3: REACTIVE IN T CELLS; CD30: REACTIVE IN OCCASIONAL CELLS LIKELY IMMUNOBLASTS; AE1/3 KERATIN: REACTIVE IN EPITHELIUM; CAM5.2 REACTIVE IN EPITHELIUM: CALPONIN: MYOEPITHELIAL CELLS INTIMATELY ASSOCIATED WITH EPITHELIUM: CYCLIND1 NEGATIVE; ANY IDEA WHAT ANY OF THIS MEANS?
doctor
Answered by Dr. Prof. Kunal Saha (2 hours later)
Brief Answer:
Further details needed

Detailed Answer:
Thanks for using the Ask a Doctor service.

I have gone carefully through the portion of immunohistopathology report that you have mentioned, but the details are inadequate. First of all, a histopathology or biopsy has been done. This report is important and it is only after correlating with this that one can comment upon. The histopathologic finding and diagnosis is important because that would act as the starting point. The next thing is that the full immunohistopathology report is needed. It needs to be known that from where exactly the immunohistopathology was taken and why. The mentioned markers CD20, keratin etc. will all be present in a normal breast biopsy. Their proportion and location matters. All I can say that it is not normal to find lymphocytes to be found in the breast pathology and therefore an infective pathology seems likely. But I would be able to comment definitively only after you upload the full reports.

I hope you understand. I would await your response.

Regards
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. Prof. Kunal Saha

General & Family Physician

Practicing since :1954

Answered : 4439 Questions

premium_optimized

The User accepted the expert's answer

Share on
JUST GOT PATHOLOGY RESULTS, BREAST BIOPSY; CD20: REACTIVE IN B

Brief Answer: Further details needed Detailed Answer: Thanks for using the Ask a Doctor service. I have gone carefully through the portion of immunohistopathology report that you have mentioned, but the details are inadequate. First of all, a histopathology or biopsy has been done. This report is important and it is only after correlating with this that one can comment upon. The histopathologic finding and diagnosis is important because that would act as the starting point. The next thing is that the full immunohistopathology report is needed. It needs to be known that from where exactly the immunohistopathology was taken and why. The mentioned markers CD20, keratin etc. will all be present in a normal breast biopsy. Their proportion and location matters. All I can say that it is not normal to find lymphocytes to be found in the breast pathology and therefore an infective pathology seems likely. But I would be able to comment definitively only after you upload the full reports. I hope you understand. I would await your response. Regards