Get your health question answered instantly from our pool of 18000+ doctors from over 80 specialties
150 Doctors Online

By proceeding, I accept the Terms and Conditions

Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

HCM Blog Instant Access to Doctors
HCM BlogQuestions Answered
HCM Blog Satisfaction

Is Nefopam safe for a pregnant woman?

Answered by
Dr.
Dr. Diptanshu Das

Pediatrician

Practicing since :2005

Answered : 3803 Questions

default
Posted on Thu, 7 Apr 2016 in Child Health
Question: Hi there...I am a midwife researching the use of Acupan (nefopam) for postnatal analgesia. I need to find out what FDA category it is. Also if midwives can prescribe it in NZ..it is classed as not safe for use when lactating ..but many drugs are..eg Tramadol...and that is frequently prescribed by anaesthetists for use post Caesarian Section...We are trying to get our anaesthetists to prescribe Acupan instead of Tramadol...please advise
Regards
XXXX
doctor
Answered by Dr. Diptanshu Das 1 hour later
Brief Answer:
Tramadol is a better alternative.

Detailed Answer:
Nefopam Hydrochloride belongs to FDA category D or X and is not recommended for pregnant women. Moreover, evidence suggests that nefopam is excreted in human milk and hence is not advocated unless the benefits outweigh the risks.

Tramadol on the other hand comes under FDA Category C and with usual maternal dosage, the amount excreted into breastmilk is much less than the dose given to newborn infants for analgesia. Tramadol is unlikely to adversely affect nursing infant and is acceptable to use during breastfeeding.

So, in a nutshell, I find no justification to shift to Acupan from Tramadol. However, I would suggest considering Morphine and other opioids for postnatal analgesia if you really want to change over.

Let me know if I could help further.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
premium_optimized

The User accepted the expert's answer

Share on
Question is related to
Drug/Medication ,   ,  
Medical Topics

Recent questions on  Nefopam

doctor1 MD

I have stage 4 endometriosis with chronic abdominal pain. I am 40. I have had multiple operations, the most recent a couple of months ago. I am on...

doctor1 MD

Hi. six weeks ago I was admitted to hospital with appendicitis, where I was treated with IV antibiotics. I also have very severe, very brittle...

doctor1 MD

I have chronic hiccups . They are getting worse. At times I can't catch my breath and have to force myself to cough to get my breath back. Have...

doctor1 MD

I am a 22 year old female who does a manual job and is usually fit and healthy. I ve suffered with abdominal pain for 6 months, beginning with...