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I am taking Pyridostigmi Extended Release 180 Mg and crushed

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Posted on Fri, 8 Feb 2019
Question: I am taking Pyridostigmi Extended Release 180 Mg and crushed a pill so I could take it. Now I found out I should not have done that what are the effects going to be on me. I expected it to last 12 hrs what can I expect it to last?
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Answered by Dr. Dorina Gurabardhi (1 hour later)
Brief Answer:
Probably the effect of medicine will be shorter because you crushed the pil

Detailed Answer:
Hello dear and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Pyridostigmine is used to improve muscle strength in muscle disease.

The effect of Pyridostigmine start working 30 to 60 minutes after you take the medication.

The effect of this medication will last at least six hours.

You should not crush the pill.

By crushing the pill you shorten the period of effect of the medication.

The period of effect of the medication can be at least 4 hours in this case based on daily practice.

Other possible side effects can be nausea and vomiting.

Hope I have answered your query. Let me know if I can assist you further.

Above answer was peer-reviewed by : Dr. Nagamani Ng
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Answered by
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Dr. Dorina Gurabardhi

General & Family Physician

Practicing since :2013

Answered : 9916 Questions

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I am taking Pyridostigmi Extended Release 180 Mg and crushed

Brief Answer: Probably the effect of medicine will be shorter because you crushed the pil Detailed Answer: Hello dear and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Pyridostigmine is used to improve muscle strength in muscle disease. The effect of Pyridostigmine start working 30 to 60 minutes after you take the medication. The effect of this medication will last at least six hours. You should not crush the pill. By crushing the pill you shorten the period of effect of the medication. The period of effect of the medication can be at least 4 hours in this case based on daily practice. Other possible side effects can be nausea and vomiting. Hope I have answered your query. Let me know if I can assist you further.