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Hi I Am On 50mg Zoloft Daily And Work Out

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Posted on Tue, 31 Mar 2020
Question: Hi I am on 50mg Zoloft Daily and work out often. I want to take a Pre workout which I have done in the past. It is a non stim pre workout with the main ingredient being L-citrulline, 2.5 grams. Will doing this hinder the effects of Zoloft and the progress I have made with the drug? Any interactions?Thanks in advance.
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Answered by Dr. Aaron Branch (46 minutes later)
Brief Answer:
No known interactions

Detailed Answer:
Hello, I'm Dr. Branch, thanks for using 'Ask a Doctor'.

The only interactions I have read about with L-Citrulline are with medications that increase blood flow to the heart, or decrease blood pressure, since L-Citrulline also has these effects. Otherwise, there are no known interactions, and with it being an amino acid, I would not expect any other interactions with medications, including with Zoloft. I would not be concerned about taking it (within recommended doses) with your Zoloft.

I hope that helps, please let me know if you have any other questions about that, and I would be glad to discuss it with you further.
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Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Answered by
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Dr. Aaron Branch

General & Family Physician

Practicing since :2011

Answered : 1223 Questions

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Hi I Am On 50mg Zoloft Daily And Work Out

Brief Answer: No known interactions Detailed Answer: Hello, I'm Dr. Branch, thanks for using 'Ask a Doctor'. The only interactions I have read about with L-Citrulline are with medications that increase blood flow to the heart, or decrease blood pressure, since L-Citrulline also has these effects. Otherwise, there are no known interactions, and with it being an amino acid, I would not expect any other interactions with medications, including with Zoloft. I would not be concerned about taking it (within recommended doses) with your Zoloft. I hope that helps, please let me know if you have any other questions about that, and I would be glad to discuss it with you further.