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Hello My Father Is 100 Years Old And Was Diognised
Question: Hello
my father is 100 years old and was diognised in 2004 with local prostate cancer and since then he was on lupron or zoladex injection every 3 months and casodex was added in 2016 the last 24 months his psa started climbing from 23 al the way to 84 . His doctor suggested that he should go for another line of hormone therapy (minimized dose of xtandi 2 40mg cpsules a day) but giving to the cercumstances of his major health a i have concerns against a second line of therapy, my father has heart desease and a border line of renal function and he is bed ridden since late 2017 and is on oxygen support when sleeping.
Is going for a second line of treatment at this age and this health condition helpful ( minimized dose) or it will do more harm than benifit? and if we decided to not go for the treatment what we should expect in the matter of pain and tumor progress and life expectancy?
Thank you
P.S he can not do any ct or bt scan due to his renal function
attached are his last blood tests
thank you
Yaqoub
my father is 100 years old and was diognised in 2004 with local prostate cancer and since then he was on lupron or zoladex injection every 3 months and casodex was added in 2016 the last 24 months his psa started climbing from 23 al the way to 84 . His doctor suggested that he should go for another line of hormone therapy (minimized dose of xtandi 2 40mg cpsules a day) but giving to the cercumstances of his major health a i have concerns against a second line of therapy, my father has heart desease and a border line of renal function and he is bed ridden since late 2017 and is on oxygen support when sleeping.
Is going for a second line of treatment at this age and this health condition helpful ( minimized dose) or it will do more harm than benifit? and if we decided to not go for the treatment what we should expect in the matter of pain and tumor progress and life expectancy?
Thank you
P.S he can not do any ct or bt scan due to his renal function
attached are his last blood tests
thank you
Yaqoub
Brief Answer:
Xtandi can be tried
Detailed Answer:
Hi
Thanks for your query.
I understand your concerns. As the disease is relentlessly progressive, life expectancy is going to be compromised by it. To halt disease progression, we should try any other hormonal therapy. Xtandi at lower dose can surely be tried.
Xtandi can cause muscle weakness, pains and aches and seizures in 1% cases. But even then, its efficacy is surely there. Considering his history, I think there's a good likelihood of disease response.
But it will be difficult to predict in an individual patient what will be the life expectancy with or without xtandi. We can only say that it has the potential to increase life expectancy.
Hope this helps.
Regards
Xtandi can be tried
Detailed Answer:
Hi
Thanks for your query.
I understand your concerns. As the disease is relentlessly progressive, life expectancy is going to be compromised by it. To halt disease progression, we should try any other hormonal therapy. Xtandi at lower dose can surely be tried.
Xtandi can cause muscle weakness, pains and aches and seizures in 1% cases. But even then, its efficacy is surely there. Considering his history, I think there's a good likelihood of disease response.
But it will be difficult to predict in an individual patient what will be the life expectancy with or without xtandi. We can only say that it has the potential to increase life expectancy.
Hope this helps.
Regards
Above answer was peer-reviewed by :
Dr. Vaishalee Punj
Thank you for you answer doctor
I have 2 questions to follow you up with.
How low can an xtandi dosage be given? Is one capsule a day is effective?
Can we postpone trying the xtandi until symptoms show on father since he is asymptomatic or it will be too late then?
Thank you again
I have 2 questions to follow you up with.
How low can an xtandi dosage be given? Is one capsule a day is effective?
Can we postpone trying the xtandi until symptoms show on father since he is asymptomatic or it will be too late then?
Thank you again
Brief Answer:
One capsule is too low
Detailed Answer:
I don't think we should go below 2 capsules a day.
As the PSA is quite high, immediate treatment is recommended.
Regards
One capsule is too low
Detailed Answer:
I don't think we should go below 2 capsules a day.
As the PSA is quite high, immediate treatment is recommended.
Regards
Note: For further queries related to kidney problems Click here.
Above answer was peer-reviewed by :
Dr. Yogesh D
Answered by
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