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Good Day, {Background} I Have Marfan Syndrome And Have Been

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Posted on Sat, 23 Nov 2019
Question: Good day,

{Background}
I have Marfan Syndrome and have been struggling with my Bowls since I can remember. When I was +-19 (1997) I had to get a Hemeroid oppertaion because of eating too much starch, I was told... It all got stuck for 3 days basically and I tore myself going to the toilet.

My main problem that been getting worse, is this: Every time I eat, anything, I always have to run to the toilet. About 3-5 times daily. Evertime it is a full once of ejection. The main issue is that I will overheat in my abdomen, by an extreme! I Sometimes forget why I overheat, then I have to go ly on my back and I can hear my stomach glug, glug, glug as the food moves.

Then time for toilet. This repeats about twice before my overheating stops.

Is it possible because of the Marfan, Pectus Escavatum that I am pushing down on my abdomen and trapping blood or food, Until I move?

Thank you so much for any advise.

Hennie

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Follow up: Dr. Ramesh Kumar (0 minute later)
Good day,

{Background}
I have Marfan Syndrome and have been struggling with my Bowls since I can remember. When I was +-19 (1997) I had to get a Hemeroid oppertaion because of eating too much starch, I was told... It all got stuck for 3 days basically and I tore myself going to the toilet.

My main problem that been getting worse, is this: Every time I eat, anything, I always have to run to the toilet. About 3-5 times daily. Evertime it is a full once of ejection. The main issue is that I will overheat in my abdomen, by an extreme! I Sometimes forget why I overheat, then I have to go ly on my back and I can hear my stomach glug, glug, glug as the food moves.

Then time for toilet. This repeats about twice before my overheating stops.

Is it possible because of the Marfan, Pectus Escavatum that I am pushing down on my abdomen and trapping blood or food, Until I move?

Thank you so much for any advise.

Hennie

doctor
Answered by Dr. Ramesh Kumar (1 hour later)
Brief Answer:
Need few details.

Detailed Answer:
Hello and thanks for choosing "Ask a Doctor" service for your query,
Have seen your details,

Is it possible because of the Marfan, Pectus Escavatum that I am pushing down on my abdomen and trapping blood or food, Until I move?-I don't think this is the case.


My main problem that been getting worse, is this: Every time I eat- Firstly you have not mentioned the duration of your problem.There are two possibilities.
1)If problem is short term(few weeks) this could be due to gastroenteritis.All your symptoms are classical symptoms of gastroenteritis.In gastroenteritis there is inflammation of intestine due to viral bacterial or protozoal infection.Gurgling in stomach running to washroom just after eating are classical signs of gastroenteritis.
2)If this problem is there for months/years it could be irritable bowel syndrome. However IBS is a diagnosis of exclusion as there is no test to confirm you have IBS,It means that when you have nothing or all your investigations are normal you are labeled as having IBS. It is a common disorder affecting the large intestine is the Irritable Bowel Syndrome. Abdominal pain, bloating, gas frequent defecation are some of the signs and symptoms of IBS. Foods, stress and other diseases can trigger the problem.

So please provide with details of time,Investigation and medications tried by you and dosages also.
waiting.
Above answer was peer-reviewed by : Dr. Prasad
doctor
doctor
Answered by Dr. Ramesh Kumar (0 minute later)
Brief Answer:
Need few details.

Detailed Answer:
Hello and thanks for choosing "Ask a Doctor" service for your query,
Have seen your details,

Is it possible because of the Marfan, Pectus Escavatum that I am pushing down on my abdomen and trapping blood or food, Until I move?-I don't think this is the case.


My main problem that been getting worse, is this: Every time I eat- Firstly you have not mentioned the duration of your problem.There are two possibilities.
1)If problem is short term(few weeks) this could be due to gastroenteritis.All your symptoms are classical symptoms of gastroenteritis.In gastroenteritis there is inflammation of intestine due to viral bacterial or protozoal infection.Gurgling in stomach running to washroom just after eating are classical signs of gastroenteritis.
2)If this problem is there for months/years it could be irritable bowel syndrome. However IBS is a diagnosis of exclusion as there is no test to confirm you have IBS,It means that when you have nothing or all your investigations are normal you are labeled as having IBS. It is a common disorder affecting the large intestine is the Irritable Bowel Syndrome. Abdominal pain, bloating, gas frequent defecation are some of the signs and symptoms of IBS. Foods, stress and other diseases can trigger the problem.

So please provide with details of time,Investigation and medications tried by you and dosages also.
waiting.
Above answer was peer-reviewed by : Dr. Prasad
doctor
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Follow up: Dr. Ramesh Kumar (19 hours later)
Good day,

thank you for the help so far.

It has been a long term problem. I usually wake up in the middle of the night soaked in sweat. Then i have to go to the toilet.

Abdominal pain, bloating, gas frequent defecation - all of those symptoms

Investigations - very painful abdomen when a doctor presses down on it.

No medication used for it.

I was diagnosed with FibroMyalgia in 2008 as part of the Marfan. Apologies for not mentioning that.

I have noticed eating salad or fish in the evenings helps.

Thank you for you time
default
Follow up: Dr. Ramesh Kumar (0 minute later)
Good day,

thank you for the help so far.

It has been a long term problem. I usually wake up in the middle of the night soaked in sweat. Then i have to go to the toilet.

Abdominal pain, bloating, gas frequent defecation - all of those symptoms

Investigations - very painful abdomen when a doctor presses down on it.

No medication used for it.

I was diagnosed with FibroMyalgia in 2008 as part of the Marfan. Apologies for not mentioning that.

I have noticed eating salad or fish in the evenings helps.

Thank you for you time
doctor
Answered by Dr. Ramesh Kumar (2 hours later)
Brief Answer:
Very likely case of IBS.

Detailed Answer:
Hello again,
Very likely you are suffering from IBS..Firstly small briefing for Irritable bowel syndrome and why every patient is a unique case when we deal with IBS.In IBS there is some problem in the functional ability of the gut that leads to the symptoms of irritable bowel syndrome. The structure of the intestines is normal, only functional abnormality occurs in this condition.So frankly speaking  (IBS) represents a functional disorder of gastrointestinal tract without the presence of an anatomic defect.
Recent studies by French scientists have  indicated that the most important mechanisms include visceral sensitivity, abnormal gut motility and autonomous nervous system dysfunction. The interactions between these three mechanisms make bowel's function susceptible to many exogenous and endogenous factors like gastrointestinal flora, feeding and psychosocial factors.
Further  data indicate that according to the above mechanisms, the influence of genetic factors and polymorphisms of human DNA in the development of IBS is equally important.
So in lay mans language till date we are not sure whats the exact cause of this problem.So the million dollar question is how to repair a system when you don't know which part of it is faulty(Some says it can be brain other says it can be hormone anxiety age etc etc).  Some patients have symptoms of unformed stools some have  bloating and some may have severe  constipation.  Some patients  have occasional symptoms whereas others may have symptoms for a long period of time.So as seen above every patient is different.Intensity of symptoms in every patient is different as so is the response to medicines and life style change.A patient may respond good to one medication while other patient is totally unresponsive to the same.
Our goal-Every drug is not effective in every patient so we have to try different therapies till we find the drug which suits best our patient.All the below mentioned drugs slows down motility of intestines hence will decrease both frequency of motions as well as will increase your power to control them.

Dicyclomine is an anticholinergic drug.An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system. Anticholinergics inhibit parasympathetic nerve impulses by selectively blocking the binding of the neurotransmitter acetylcholine to its receptor in nerve cells.
Mebeverine is an antispasmodic medicine and is very useful in IBS and is well tolerated by patient with minimal side effects. Mebeverine works on certain muscles in the wall of your intestines, causing them to relax. Clidinium bromide is an anticholinergic (specifically a  
It may help symptoms of frequent stools.
Chlordiazepoxide works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.Can be used in combination with above mentioned medicines.

Ask your Gastroenterologist to start you initially on  clidinium bromide and mebeverine  combination initially for 21 days.
Consult your gastroenterologist and discuss with him the answer.
If I've provided useful and helpful information to your questions could you do me a huge favor by CLOSING THE QUERY being sure to include several fine words of feedback. Again, many thanks for submitting your inquiry and please let me know how things turn out.
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
doctor
Answered by Dr. Ramesh Kumar (0 minute later)
Brief Answer:
Very likely case of IBS.

Detailed Answer:
Hello again,
Very likely you are suffering from IBS..Firstly small briefing for Irritable bowel syndrome and why every patient is a unique case when we deal with IBS.In IBS there is some problem in the functional ability of the gut that leads to the symptoms of irritable bowel syndrome. The structure of the intestines is normal, only functional abnormality occurs in this condition.So frankly speaking  (IBS) represents a functional disorder of gastrointestinal tract without the presence of an anatomic defect.
Recent studies by French scientists have  indicated that the most important mechanisms include visceral sensitivity, abnormal gut motility and autonomous nervous system dysfunction. The interactions between these three mechanisms make bowel's function susceptible to many exogenous and endogenous factors like gastrointestinal flora, feeding and psychosocial factors.
Further  data indicate that according to the above mechanisms, the influence of genetic factors and polymorphisms of human DNA in the development of IBS is equally important.
So in lay mans language till date we are not sure whats the exact cause of this problem.So the million dollar question is how to repair a system when you don't know which part of it is faulty(Some says it can be brain other says it can be hormone anxiety age etc etc).  Some patients have symptoms of unformed stools some have  bloating and some may have severe  constipation.  Some patients  have occasional symptoms whereas others may have symptoms for a long period of time.So as seen above every patient is different.Intensity of symptoms in every patient is different as so is the response to medicines and life style change.A patient may respond good to one medication while other patient is totally unresponsive to the same.
Our goal-Every drug is not effective in every patient so we have to try different therapies till we find the drug which suits best our patient.All the below mentioned drugs slows down motility of intestines hence will decrease both frequency of motions as well as will increase your power to control them.

Dicyclomine is an anticholinergic drug.An anticholinergic agent is a substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system. Anticholinergics inhibit parasympathetic nerve impulses by selectively blocking the binding of the neurotransmitter acetylcholine to its receptor in nerve cells.
Mebeverine is an antispasmodic medicine and is very useful in IBS and is well tolerated by patient with minimal side effects. Mebeverine works on certain muscles in the wall of your intestines, causing them to relax. Clidinium bromide is an anticholinergic (specifically a  
It may help symptoms of frequent stools.
Chlordiazepoxide works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.Can be used in combination with above mentioned medicines.

Ask your Gastroenterologist to start you initially on  clidinium bromide and mebeverine  combination initially for 21 days.
Consult your gastroenterologist and discuss with him the answer.
If I've provided useful and helpful information to your questions could you do me a huge favor by CLOSING THE QUERY being sure to include several fine words of feedback. Again, many thanks for submitting your inquiry and please let me know how things turn out.
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Yogesh D
doctor
Answered by
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Dr. Ramesh Kumar

Gastroenterologist

Practicing since :1986

Answered : 2906 Questions

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Good Day, {Background} I Have Marfan Syndrome And Have Been

Good day, {Background} I have Marfan Syndrome and have been struggling with my Bowls since I can remember. When I was +-19 (1997) I had to get a Hemeroid oppertaion because of eating too much starch, I was told... It all got stuck for 3 days basically and I tore myself going to the toilet. My main problem that been getting worse, is this: Every time I eat, anything, I always have to run to the toilet. About 3-5 times daily. Evertime it is a full once of ejection. The main issue is that I will overheat in my abdomen, by an extreme! I Sometimes forget why I overheat, then I have to go ly on my back and I can hear my stomach glug, glug, glug as the food moves. Then time for toilet. This repeats about twice before my overheating stops. Is it possible because of the Marfan, Pectus Escavatum that I am pushing down on my abdomen and trapping blood or food, Until I move? Thank you so much for any advise. Hennie