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Can We Successfully Conceive When My Wife And I Are Positive For Herpes IgG And CMV Tests?

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Posted on Fri, 23 Feb 2024
Question: Hi.. Me and my wife are trying for a baby. Since there were few miscarriages, my doctor advised me to take few blood tests. The result came positive for Herpes IgG and CMV tests for both me and my wife. I am so worried. I want to know if there is a treatment to cure Herpes permanently. Is it life threatening? I am so worried if this will cause further miscarriages? Please help solve my query. I am worried so much.
doctor
Answered by Dr. Dr. Monika Dede (1 hour later)
Brief Answer:
This is not life threatening .

Detailed Answer:

Hello,

I have read carefully your history and you should know that IgG for herpes and CMV may come positive in many individuals, who are normal and asymptomatic. So, there is no significance of positive IgG alone because it is normal and treatment is not required for you and for your wife.
This is not life threatening and not exist treatment to cure permanently the herpes.
In your case you should exclude a thyroid problem as well .

I hope my answer helps you.
Regards.
Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
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Follow up: Dr. Dr. Monika Dede (1 hour later)
Thank you very much for answering my question. As per your comments, I understand that CMV-IgG and HSV-IgM which are positive in us, does not cause miscarriages and it is not life-threatening. I will test for thyroid as well as suggested.

My another major doubt is that I have read in many websites that CMV could be passed on to the foetus during pregnancy and it will cause serious disorders like hearing loss, cerebral palsy and nervous disorders including Down syndrome.

Can you please suggest how can we prevent the transfer to the baby. Is there any solution to cure CMV-IgG completely?
doctor
Answered by Dr. Dr. Monika Dede (20 hours later)
Brief Answer:
There is no treatment to cure completely CMV IgG.

Detailed Answer:
Hello,
Thank you writing back.


Please clarify me HSV is IgM positive or just IgG positive.
You should know that CMV could cause problems in fetus during pregnancy but just in moment that is IgM positive , in acute phase, and not when just IgG is positive.
There is no treatment to cure completely CMV IgG.

I hope my answer helps you.
Regards.

Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. Dr. Monika Dede (13 hours later)
Thank you so much for your detailed clarification.

To answer your question, our HSV result is IgM positive. Is that a problem? How can it be treated?

And also CMV is IgM positive. Can you please tell what treatment are available to avoid the CMV to be transferred to the foetus. If she gets treated for CMV and HSV, will it get reactivated again during pregnancy again? What is the acute phase you mentioned? How do we know if it is acute phase or not?

How to prevent it from passing it to the baby. We do not mind ourselves being infected. Please clarify.

Thanks again
doctor
Answered by Dr. Dr. Monika Dede (32 hours later)
Brief Answer:
When IgM is positive she has acute phase of infections.

Detailed Answer:
Hello,
I am sorry for my late response.

Having a positive IgM for HSV and CMV means that your wife has an acute infection of HSV and CMV.
You should know that during the acute phase in pregnancy exist a high risk to have fetus complications and to pass the infection to tha baby.
A pregnant woman can pass CMV to her fetus following primary(acute phase) infection, or reactivation of a previous infection during pregnancy.
The only treatment in both, HSV and CMV infection are antivirals(acyclovir or valgancyclovir) according the prescription of an ID specialist.
I suggest to wait for a pregnancy when the IgM of HSV and CMV will be negative and IgG positive. It means that has passed the acute phase.

I hope my answer helps you.
Regards.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Kampana
doctor
Answered by
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Dr. Dr. Monika Dede

Infectious Diseases Specialist

Practicing since :2003

Answered : 1005 Questions

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Can We Successfully Conceive When My Wife And I Are Positive For Herpes IgG And CMV Tests?

Brief Answer: This is not life threatening . Detailed Answer: Hello, I have read carefully your history and you should know that IgG for herpes and CMV may come positive in many individuals, who are normal and asymptomatic. So, there is no significance of positive IgG alone because it is normal and treatment is not required for you and for your wife. This is not life threatening and not exist treatment to cure permanently the herpes. In your case you should exclude a thyroid problem as well . I hope my answer helps you. Regards.