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Can Long Term Use And Increased Dosage Of Mirapex Lead To Fidgeting And Squirming?

Posted on Wed, 20 Mar 2024

Question: Can long term use and increased dosage of Mirapex taken for RLS cause fidgeting, squirmming & involuntary movement?

Answered by Dr. Saumya Mittal (45 minutes later)

Brief Answer:
yes

Detailed Answer:
Hi
I am Dr Mittal.
I have read your message.
Mirapex contains pramipexole- a common medicine for RLS and Parkinsonism.
The side effect profile of the medicine does include fidgeting, squirmming & involuntary movement especially tremors.
However, it usually happens after a long term use.
I hope that helps.
Best wishes, Dr Mittal

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Saumya Mittal (38 minutes later)

So do you recommend changing to Ropinirole? Will the involuntary movement continue? I have taken 0.125mg of Mirapex for at least 20 years without side effects & doubled the dose in the last year. This is when the squirming began. It has been suggested by the head nurse at a sleep center that changing to Ropinirole is necessary & will eliminate the involuntary movement side effect. Do you concur?

Answered by Dr. Saumya Mittal (6 minutes later)

Brief Answer:
Suggestions

Detailed Answer:
Hello.
Thanks for your response.
I do agree with the nurse.
That is one way of dealing with this.
Another way would be to reduce the dose of ongoing medicine.
And a third approach would be to give both at low dose.
I usually prefer the third approach.
But it depends completely on your comfort level.
Best wishes,Dr Mittal

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Above answer was peer-reviewed by : Dr. Prasad