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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Why Is There Problem In Managing BP With Conversyl?

I have been taking 10 mg ramipril for approx 7 years with success in keeping my BP in line. Recently my doctor switched me to coversyl as the ramipril was not working. He has bumped up fron 4 to 8 mg daily and it's not working . Is there a reason he would not have just increased the ramipril. My BP avg is 145/95
Fri, 19 Dec 2014
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Neurologist 's  Response
I read your question and I understand your concern.

Ramipril and Perindopril (Coversyl) belong to the same class (ACE inhibitors), same mechanism of action and should have similar efficacy. So technically speaking no reason to expect much of a difference between them. But sometimes clinicians base their decisions also on personal experience, maybe he had very good results with Coversyl in other patients before, or has had good experience and a high regard for the quality of the drugs of the company which manufactures Coversyl.
If your blood pressure is not well controlled anymore with ACE inhibitors alone (10 mg of Ramipril or 8 of Perindopril is not a small dose), an additional drug of a different class could be added like a beta-blocker, diuretic or calcium blocker.

I hope to have been of help.
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Why Is There Problem In Managing BP With Conversyl?

I read your question and I understand your concern. Ramipril and Perindopril (Coversyl) belong to the same class (ACE inhibitors), same mechanism of action and should have similar efficacy. So technically speaking no reason to expect much of a difference between them. But sometimes clinicians base their decisions also on personal experience, maybe he had very good results with Coversyl in other patients before, or has had good experience and a high regard for the quality of the drugs of the company which manufactures Coversyl. If your blood pressure is not well controlled anymore with ACE inhibitors alone (10 mg of Ramipril or 8 of Perindopril is not a small dose), an additional drug of a different class could be added like a beta-blocker, diuretic or calcium blocker. I hope to have been of help.